Vitreoretinal lymphoma: a diagnostic challenge.

Autor: Sáenz Decker E; Servicio de Oftalmologia, Hospital Universitario Central de Asturias, Oviedo, Spain. Electronic address: elensdeck@gmail.com., García Fernández M; Servicio de Oftalmologia, Hospital Universitario Central de Asturias, Oviedo, Spain., Gómez De la Torre R; Servicio de Medicina Interna, Hospital Universitario Central de Asturias, Oviedo, Spain., Coto Hernández R; Servicio de Medicina Interna, Hospital Universitario Central de Asturias, Oviedo, Spain., Santana García LI; Servicio de Oftalmologia, Hospital Universitario Central de Asturias, Oviedo, Spain.
Jazyk: angličtina
Zdroj: Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol (Engl Ed)] 2023 Dec; Vol. 98 (12), pp. 718-722. Date of Electronic Publication: 2023 Oct 07.
DOI: 10.1016/j.oftale.2023.10.002
Abstrakt: A 66-year-old man with posterior uveitis and recurrent cystic macular edema related to possible previously treated Lyme disease is presented. Due to the recurrence of macular edema despite systemic and local corticosteroid treatment with intravitreal dexamethasone, biological treatment with Adalimumab was established. During follow-up, the patient developed bilateral subretinal lesions compatible with Vitreoretinal Lymphoma (VRL), so vitrectomy was performed, confirming the diagnosis of large B-cell lymphoma. Treatment with systemic chemotherapy with BRAM-Carmustine, Metrotexate, Ara C, and Rituximab was started with a good answer. Two years later, the patient remains without ocular or systemic recurrences. Vitreoretinal Lymphoma is a rare type of primary central nervous system lymphoma. The diagnosis is frequently delayed due to the nonspecific symptoms, which mimic chronic posterior uveitis, hence the importance with a diagnostic suspicion.
(Copyright © 2023 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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