Comparing Outcomes of Phacoemulsification and Endocyclophotocoagulation with Either Dual Blade Goniotomy (PEcK) or Two Trabecular Stents (ICE2).

Autor: El Helwe H; Department of Ophthalmology, Harvard Medical School and Mass Eye and Ear, Boston, MA, USA., Oberfeld B; Department of Ophthalmology, Harvard Medical School and Mass Eye and Ear, Boston, MA, USA., Golsoorat Pahlaviani F; Department of Ophthalmology, Harvard Medical School and Mass Eye and Ear, Boston, MA, USA., Falah H; Department of Ophthalmology, Harvard Medical School and Mass Eye and Ear, Boston, MA, USA., Trzcinski J; Department of Ophthalmology, Harvard Medical School and Mass Eye and Ear, Boston, MA, USA., Solá-Del Valle D; Department of Ophthalmology, Harvard Medical School and Mass Eye and Ear, Boston, MA, USA.
Jazyk: angličtina
Zdroj: Clinical ophthalmology (Auckland, N.Z.) [Clin Ophthalmol] 2023 Oct 03; Vol. 17, pp. 2879-2888. Date of Electronic Publication: 2023 Oct 03 (Print Publication: 2023).
DOI: 10.2147/OPTH.S431356
Abstrakt: Purpose: To compare outcomes of phacoemulsification and endocyclophotocoagulation with either dual blade goniotomy (PEcK) or two trabecular stents (ICE2).
Setting: Retrospective, nonrandomized comparative study from a level 3 triage center.
Methods: One hundred and seventy charts and a total of 1294 visits were reviewed following either PEcK or ICE2 from 2018 to 2022. One hundred and twenty-eight patients had PEcK and 42 underwent ICE2. Patients with less than 30 days of follow-up were excluded. The mean follow-up time was 505 ± 308 days. Two Kaplan-Meier curves (KM) assessed survival with ≤ baseline medications while maintaining (1) [GIC - Goal IOP Criteria] IOP ≤ goal IOP or (2) [PRC - Percent Reduction Criteria] IOP reduction ≥ 20% with 5 mmHg ≤ IOP ≤ 21 mmHg for at least two consecutive visits. IOP and medication burden reduction were compared using a paired t -test.
Results: Most patients were Caucasian (65%) and had mild-stage glaucoma (43%). The most common glaucoma type was primary open-angle glaucoma (58%). Average age was 72.2 years at the time of surgery. Mean preoperative IOP was 17.58 ± 4.98 mmHg on 3.00 ± 1.41 medications in PEcK and 15.36 ± 3.58 mmHg on 1.81 ± 1.11 medications in ICE2 (p = 0.015 for IOP; p < 0.001 for medications). Under GIC, the success rate was significantly higher in PEcK at POM6 (69% vs 46%, p < 0.001) and POY1 (63% vs 36%, p < 0.001). Under PRC, the success rate was significantly higher in PEcK at POM6 (73% vs 61%, p = 0.031) and POY1 (67% vs 50%, p = 0.028). Mean reductions at POY1 were 5.00 ± 4.31 mmHg on 1.35 ± 1.08 less medications after PEcK and 3.14 ± 2.83 mmHg on 1.01 ± 0.94 less medications after ICE2 (p < 0.001 at POY1 for IOP; p < 0.05 after POW6 for medications).
Conclusion: Both PEcK and ICE2 reduce medication and IOP from baseline, with PEcK having more favorable GIC and PRC success rates and greater IOP and medication reduction at 1 year.
Competing Interests: D. Solá-Del Valle received financial support from Allergan, an AbbVie company, for giving lectures related to the XEN Gel Stent in 2021, a device that is unrelated to this study. The authors report no other conflicts of interest in this work.
(© 2023 El Helwe et al.)
Databáze: MEDLINE
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