Proceedings from the Melanoma Research Foundation Mucosal Melanoma Meeting (December 16, 2022, New York, USA).

Autor: Wei AZ; Columbia University Irving Medical Center, New York, New York, USA., Chen LN; Columbia University Irving Medical Center, New York, New York, USA., Orloff M; Thomas Jefferson University Sidney Kimmel Cancer Center, Philadelphia, Pennsylvania, USA., Ariyan CE; Memorial Sloan Kettering Cancer Center, New York, New York, USA., Asgari M; Harvard Medical School, Boston, Massachusetts, USA., Barker CA; Memorial Sloan Kettering Cancer Center, New York, New York, USA., Buchbinder E; Dana-Farber Cancer Institute/Harvard Cancer Center, Boston, Massachusetts, USA., Chandra S; Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Couts K; University of Colorado School of Medicine, Aurora, Colorado, USA., Frumovitz MM; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Futreal A; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gershenwald JE; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Hanna EY; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Izar B; Columbia University Irving Medical Center, New York, New York, USA., LeBlanc AK; National Institute of Health, Bethesda, Maryland, USA., Leitao MM Jr; Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, New York, USA., Lipson EJ; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Liu D; Dana-Farber Cancer Institute/Harvard Cancer Center, Boston, Massachusetts, USA., McCarter M; University of Colorado School of Medicine, Aurora, Colorado, USA., McQuade JL; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Najjar Y; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, Pennsylvania, USA., Rapisuwon S; Georgetown University/MedStar Health, Washington, DC, USA., Selig S; Melanoma Research Foundation, CURE OM, Washington, DC, USA., Shoushtari AN; Memorial Sloan Kettering Cancer Center, New York, New York, USA., Yeh I; University of California, San Francisco, San Francisco, California, USA., Schwartz GK; Case Comprehensive Cancer Center, Cleveland, Ohio, USA., Guo J; Peking University Cancer Hospital & Institute, Beijing, China., Patel SP; The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Carvajal RD; Northwell Health Cancer Institute, New Hyde Park, New York, USA.
Jazyk: angličtina
Zdroj: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2023 Nov; Vol. 36 (6), pp. 542-556. Date of Electronic Publication: 2023 Oct 07.
DOI: 10.1111/pcmr.13139
Abstrakt: Mucosal melanoma remains a rare cancer with high mortality and a paucity of therapeutic options. This is due in significant part to its low incidence leading to limited patient access to expert care and downstream clinical/basic science data for research interrogation. Clinical challenges such as delayed and at times inaccurate diagnoses, and lack of consensus tumor staging have added to the suboptimal outcomes for these patients. Clinical trials, while promising, have been difficult to activate and accrue. While individual institutions and investigators have attempted to seek solutions to such problems, international, national, and local partnership may provide the keys to more efficient and innovative paths forward. Furthermore, a mucosal melanoma coalition would provide a potential network for patients and caregivers to seek expert opinion and advice. The Melanoma Research Foundation Mucosal Melanoma Meeting (December 16, 2022, New York, USA) highlighted the current clinical challenges faced by patients, providers, and scientists, identified current and future clinical trial investigations in this rare disease space, and aimed to increase national and international collaboration among the mucosal melanoma community in an effort to improve patient outcomes. The included proceedings highlight the clinical challenges of mucosal melanoma, global clinical trial experience, basic science advances in mucosal melanoma, and future directions, including the creation of shared rare tumor registries and enhanced collaborations.
(© 2023 The Authors. Pigment Cell & Melanoma Research published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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