Trends in Repeat Opioid Analgesic Prescription Utilization for Acute Pain in Children: 2013-2018.

Autor: Nair AA; Department of Pharmaceutical Health Outcomes and Policy (AA Nair, RR Aparasu, M Johnson, and H Chen), College of Pharmacy, University of Houston, Houston, Tex., Placencia JL; Department of Pharmacy (JL Placencia), Texas Children's Hospital, Houston, Tex., Farber HJ; Department of Pediatrics (HJ Farber), Section of Pulmonology, Baylor College of Medicine and Texas Children's Hospital, Houston, Tex., Aparasu RR; Department of Pharmaceutical Health Outcomes and Policy (AA Nair, RR Aparasu, M Johnson, and H Chen), College of Pharmacy, University of Houston, Houston, Tex., Johnson M; Department of Pharmaceutical Health Outcomes and Policy (AA Nair, RR Aparasu, M Johnson, and H Chen), College of Pharmacy, University of Houston, Houston, Tex., Chen H; Department of Pharmaceutical Health Outcomes and Policy (AA Nair, RR Aparasu, M Johnson, and H Chen), College of Pharmacy, University of Houston, Houston, Tex. Electronic address: hchen25@central.uh.edu.
Jazyk: angličtina
Zdroj: Academic pediatrics [Acad Pediatr] 2024 Jul; Vol. 24 (5), pp. 776-782. Date of Electronic Publication: 2023 Oct 04.
DOI: 10.1016/j.acap.2023.09.020
Abstrakt: Objective: Our study examined the change in repeat opioid analgesic prescription trends in children and adolescents experiencing acute pain between 2013 and 2018.
Methods: Eligible individuals were children and adolescents between 1 and 17 years of age enrolled in a Medicaid Managed Care plan and filled an incident opioid analgesic prescription from 2013 to 2018. A repeat opioid prescription was defined as receiving a subsequent opioid prescription within 30 days from the end of the incident opioid prescription. A generalized linear regression analysis was conducted to examine changes in repeat opioid analgesic dispensing over time at quarterly intervals from January 1, 2013, to December 31, 2018.
Results: The cohort comprised 17,086 children and adolescents receiving an incident opioid analgesic. Of these, 1780 (10.4%) filled a repeat opioid analgesic prescription. There was a significant decline in the repeat opioid analgesic trend from 11.5% in Q1 2013 to 9.6% in Q4 2018. Stratified analyses by age, sex, and race and ethnicity in a sub-cohort of patients undergoing surgical procedures showed that a significant decline in repeat opioid utilization over time has been observed in all racial/ethnic groups stratified by age and sex, with the most significant decline found in non-Hispanic White children and Hispanic adolescents. At the end of the 6-year follow-up, the racial and ethnic variations in repeat opioid utilization associated with surgical procedures had significantly reduced in children yet persisted among adolescents.
Conclusions: Approximately 10% of incident pediatric opioid analgesic recipients received a repeat opioid prescription. There has been a moderate but steady decline (∼7% per quarter) in repeat opioid analgesic utilization between 2013 and 2018.
Competing Interests: Declaration of Competing Interest The authors indicate that there is no potential conflict of interest to disclose.
(Copyright © 2024 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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