New insights into the pathogenesis and transmission of Brucella pinnipedialis : systemic infection in two bottlenose dolphins ( Tursiops truncatus ).

Autor:	Vargas-Castro I; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain.; Animal Health Department, Veterinary School, Complutense University of Madrid , Madrid, Spain., Crespo-Picazo JL; 3 Fundación Oceanogràfic. Oceanogràfic. Ciudad de las Artes y las Ciencias , Valencia, Spain., Fayos M; Centro de Recuperación de Fauna Silvestre de Cantabria , Santander, Spain., Jiménez-Martínez MdlÁ; Department of Animal Medicine and Surgery, Veterinary Faculty, Complutense University of Madrid , Madrid, Spain., Torre-Fuentes L; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain., Álvarez J; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain.; Animal Health Department, Veterinary School, Complutense University of Madrid , Madrid, Spain., Moura AE; Museum and Institute of Zoology, Polish Academy of Sciences , Warsaw, Poland., Hernández M; Laboratory of Molecular Biology and Microbiology, Instituto Tecnológico Agrario de Castilla y León , Valladolid, Spain., Buendía A; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain., Barroso-Arévalo S; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain.; Animal Health Department, Veterinary School, Complutense University of Madrid , Madrid, Spain., García-Seco T; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain., Pérez-Sancho M; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain.; Animal Health Department, Veterinary School, Complutense University of Madrid , Madrid, Spain., De Miguel MJ; Departamento de Ciencia Animal, Centro de Investigación y Tecnología Agroalimentaria de Aragón (CITA) - Instituto Agroalimentario de Aragón-IA2 (CITA-Universidad de Zaragoza) , Zaragoza, España, Spain., Andrés-Barranco S; Departamento de Ciencia Animal, Centro de Investigación y Tecnología Agroalimentaria de Aragón (CITA) - Instituto Agroalimentario de Aragón-IA2 (CITA-Universidad de Zaragoza) , Zaragoza, España, Spain., Marco-Cabedo V; 3 Fundación Oceanogràfic. Oceanogràfic. Ciudad de las Artes y las Ciencias , Valencia, Spain., Peñin-Villahoz G; Centro de Recuperación de Fauna Silvestre de Cantabria , Santander, Spain., Muñoz PM; Departamento de Ciencia Animal, Centro de Investigación y Tecnología Agroalimentaria de Aragón (CITA) - Instituto Agroalimentario de Aragón-IA2 (CITA-Universidad de Zaragoza) , Zaragoza, España, Spain., Domínguez L; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain.; Animal Health Department, Veterinary School, Complutense University of Madrid , Madrid, Spain., García-Párraga D; 3 Fundación Oceanogràfic. Oceanogràfic. Ciudad de las Artes y las Ciencias , Valencia, Spain., Sánchez-Vizcaíno JM; VISAVET Health Surveillance Centre, Complutense University of Madrid , Madrid, Spain.; Animal Health Department, Veterinary School, Complutense University of Madrid , Madrid, Spain.
Jazyk:	angličtina
Zdroj:	Microbiology spectrum [Microbiol Spectr] 2023 Dec 12; Vol. 11 (6), pp. e0199723. Date of Electronic Publication: 2023 Oct 06.
DOI:	10.1128/spectrum.01997-23
Abstrakt:	Importance: Brucella spp. are zoonotic pathogens that can affect both terrestrial and marine mammals. Brucella ceti has been identified in various cetacean species, but only one sequence type (ST27) has been reported in humans. However, it is important to conduct surveillance studies to better understand the impact of marine Brucella species on marine mammals, a typically understudied host group. Here, we describe a systemic infection by two related strains of Brucella pinnipedialis (ST25) in a couple of live-stranded bottlenose dolphins, with more severe lesions in the younger animal. Furthermore, B. pinnipedialis was first detected in milk from a female cetacean that stranded with its offspring. Our study reveals novel insights into the epidemiology and pathological consequences of B. pinnipedialis infections in cetaceans, emphasizing the crucial importance of ongoing surveillance and accurate diagnosis to understand the impact of this pathogen on marine mammal populations. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
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