The prevalence and risk factors of functional dyspepsia among adults in low- and middle-income countries: An international cross-sectional study.

Autor:	Arnaout AY; Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic., Alhejazi TJ; Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic., Nerabani Y; Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic., Hamdan O; Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic., Arnaout K; Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic., Arnaout I; Faculty of Medicine, University of Aleppo, Aleppo, Syrian Arab Republic., Aljarad Z; MD, MSc, PhD Gastroenterologist, University of Aleppo, Aleppo, Syrian Arab Republic.
Jazyk:	angličtina
Zdroj:	Medicine [Medicine (Baltimore)] 2023 Oct 06; Vol. 102 (40), pp. e35437.
DOI:	10.1097/MD.0000000000035437
Abstrakt:	Dyspepsia is one of the most common chronic digestive diseases, which is due to underlying organic causes that can be detected, or causes that cannot be detected called functional dyspepsia (FD). There is no epidemiological study to date that measures the prevalence and risk factors of the FD in low- and middle-income countries, so this international cross-sectional study was conducted in 15 low- and middle-income countries from data previously published its protocol NCT05340400. Participants were recruited in the period from 22/April/2022 to 14/June/2022. The diagnosis of the FD was according to clinical manifestations. We determined the physical activity, daily stress, and fatigue of the participants. A large number of collaborators were chosen from different regions and institutions within each country to achieve diversity within the sample and reduce the probability of bias. Our study concluded that the prevalence of FD is much higher in low- and middle-income countries 37.9% [6.2%-44.2%], compared to high-income countries 10% [8%-12%], with a higher rate among the Afro-Caribbean race 47.9%. Sudan obtained the highest prevalence 44.3%, then Egypt 41.4%, while the lowest prevalence was in Algeria 25.7%. Moreover, there are many risk factors, including modifiable ones, such as severe stress, chronic fatigue, smoking, abnormal BMI, insufficient or too many hours of sleep, and previous infection with Covid-19, and non-modifiable ones such as advanced age, chronic diseases, and female sex. Highlighting the prevalence and increasing risk factors of FD in low- and middle-income countries should draw the attention of those responsible for health care in these countries and reduce the risk factors. Competing Interests: The authors have no funding and conflicts of interest to disclose. (Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu