Adverse effects of delta-9-tetrahydrocannabinol on sickle red blood cells.

Autor: Hatem A; Sorbonne Université, CNRS, UMR8227 LBI2M, Station Biologique de Roscoff, Roscoff, France.; Laboratory of Excellence GR-Ex, Paris, France., Esperti S; Laboratory LIBM EA7424, Vascular Biology and Red Blood Cell Team, University of Lyon, Lyon, France., Murciano N; Research and Development, Nanion Technologies, Munich, Germany.; Theoretical Medicine and Biosciences, Saarland University, Homburg, Germany., Qiao M; Theoretical Medicine and Biosciences, Saarland University, Homburg, Germany.; Experimental Physics, Saarland University, Saarbrücken, Germany., Giustina Rotordam M; Research and Development, Nanion Technologies, Munich, Germany., Becker N; Research and Development, Nanion Technologies, Munich, Germany., Nader E; Laboratory LIBM EA7424, Vascular Biology and Red Blood Cell Team, University of Lyon, Lyon, France., Maurer F; Experimental Physics, Saarland University, Saarbrücken, Germany., Pérès L; Sorbonne Université, CNRS, UMR8227 LBI2M, Station Biologique de Roscoff, Roscoff, France.; Laboratory of Excellence GR-Ex, Paris, France., Bouyer G; Sorbonne Université, CNRS, UMR8227 LBI2M, Station Biologique de Roscoff, Roscoff, France.; Laboratory of Excellence GR-Ex, Paris, France., Kaestner L; Theoretical Medicine and Biosciences, Saarland University, Homburg, Germany.; Experimental Physics, Saarland University, Saarbrücken, Germany., Connes P; Laboratory LIBM EA7424, Vascular Biology and Red Blood Cell Team, University of Lyon, Lyon, France., Egée S; Sorbonne Université, CNRS, UMR8227 LBI2M, Station Biologique de Roscoff, Roscoff, France.; Laboratory of Excellence GR-Ex, Paris, France.
Jazyk: angličtina
Zdroj: American journal of hematology [Am J Hematol] 2023 Dec; Vol. 98 (12), pp. E383-E386. Date of Electronic Publication: 2023 Oct 06.
DOI: 10.1002/ajh.27109
Abstrakt: THC triggers a pronounced entry of Ca 2+ , which may be deleterious, into sickle cell red blood cells via activation of the TRPV2 channel.
(© 2023 Wiley Periodicals LLC.)
Databáze: MEDLINE
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