Prevalence of Neurolathyrism and its associated factors in Grass pea cultivation areas of Dawunt District, North-eastern Ethiopia; 2022: a community based multilevel analysis.

Autor: Bimerew M; Department of Pediatric and Child Health Nursing, College of Medicine and Health Science, Injibara University, Injibara, Ethiopia. mebiget@gmail.com., Gebremeskel T; Department of Human Anatomy, College of Health Science, Woldia University, Woldia, Ethiopia., Beletew B; Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia., Ayalneh M; Department of Pediatric and Child Health Nursing, College of Medicine and Health Science, Injibara University, Injibara, Ethiopia., Ayaliew W; Department of Plant Biotechnology, Woldia University, Woldia, Ethiopia., Wodaje M; Department of Midwifery, College of Health Science, Woldia University, Woldia, Ethiopia.
Jazyk: angličtina
Zdroj: BMC neurology [BMC Neurol] 2023 Oct 05; Vol. 23 (1), pp. 357. Date of Electronic Publication: 2023 Oct 05.
DOI: 10.1186/s12883-023-03379-0
Abstrakt: Introduction: Neurolathyrism is an upper motor neuron disorder characterized by spastic paraparesis, which is caused by the prolonged over-consumption of grass pea. It is a devastating disease with great impacts on physical, social, mental, and economical health.
Objective: To determine the prevalence of neurolathyrism and its associated factors in grass pea cultivation areas of Dawunt wereda.
Methods: Community based cross-sectional study design was conducted from February 01- March 30, 2021 on 631 Households with a total of 3,350 individuals. Two-stage random sampling technique was used to select participants. Multilevel binary logistic regression was used to identify factors associated with neurolathyrism. Statistical significance was declared at p < 0.05; and AOR with 95% CI was used to interpret the results.
Results: The household and population level prevalence of neurolathyrism in Dawunt district were 9.2% (7.2-11.7%) and 2.4% (2.0-2.3.0%) respectively. Age (AOR = 7.4 ( 2.6-20.6)), male sex (AOR = 7.8 (3.9, 15.4)), and marital status (AOR = 4.0 (1.3-12.8)) were the individual level variables; family size (AOR = 12.6 (3.0-52.8)), annual grass pea production (AOR = 5.0 (2.3-11.0)), ever feeding only grass pea (AOR = 8.8(3.5-22.2)), ever feeding immature seeds of grass pea (AOR = 6.28 (2.80, 14.08)), high grass pea to other cereals mixing ratio (> 3:1) (AOR = 6.1 (1.1, 33.5)) were the household level variables found to have significant association with neurolathyrism.
Conclusion: The prevalence of neurolathyrism was found to be high. Ever feeding only grass pea, Grass pea to other cereals mixing ratio (using ratio of 1:1 or more), and Ever feeding immature grass pea seeds were the modifiable risk factors for neurolathyrism.
(© 2023. BioMed Central Ltd., part of Springer Nature.)
Databáze: MEDLINE
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