Moderately hypofractionated post-operative radiation therapy for breast cancer: preferences amongst radiation oncologists from countries in Latin America and the Caribbean.

Autor:	Marta GN; Department of Radiation Oncology, Hospital Sírio-Libanês, Sao Paulo, Brazil.; Latin American Cooperative Oncology Group (LACOG), Brazil., Moraes FY; Latin American Cooperative Oncology Group (LACOG), Brazil.; Department of Oncology, Division of Radiation Oncology, Queen's University - Kingston Health Science Centre, Kingston, ON, Canada., de Oliveira Franco RC; Gerald Bronfman Department of Oncology - Radiation Oncology Department - McGill University, Canada., de Andrade Carvalho H; Latin American Cooperative Oncology Group (LACOG), Brazil.; Department of Radiology and Oncology - Radiotherapy Division - Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Gouveia AG; Latin American Cooperative Oncology Group (LACOG), Brazil.; Juravinski Cancer Centre, Department of Oncology, Division of Radiation Oncology, Hamilton, ON, Canada., de Lima Gössling GC; Latin American Cooperative Oncology Group (LACOG), Brazil., de Jesus RG; Latin American Cooperative Oncology Group (LACOG), Brazil., Ferraris G; Centro Radioterapia Dean Funes, Córodoba, Argentina., Schuffenegger PM; Latin American Cooperative Oncology Group (LACOG), Brazil.; Radiation Oncology Unit, Department of Hematology - Oncology, Pontificia Universidad Catolica de Chile, Chile., Bardales GS; Instituto Nacional Enfermedades Neoplásicas, Peru., Chacón MAP; Medica Sur, Radiation Oncology Department, Mexico., Murillo R; Centro Javeriano de Oncología, Hospital Universitario San Ignacio, Bogota, Colombia.; Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia., Sánchez LEM; Instituto Nacional del Cáncer Rosa De Tavares (INCART), Savia Care Centro Avanzado de Radioterapia, Centro Gamma Knife Dominicano, Dominican Republic., Gamarra-Cabezas E; Departamento de Radio-Oncología, Instituto Oncológico Nacional 'Dr. Juan Tanca Marengo'.; Sociedad de Lucha Contra el Cáncer (SOLCA), Guayaquil, Ecuador., Rosa AA; Latin American Cooperative Oncology Group (LACOG), Brazil.; Oncoclinicas Salvador - Hospital Santa Izabel., da Silva MF; Latin American Cooperative Oncology Group (LACOG), Brazil.; Santa Maria Federal University, Santa Maria, RS, Brazil.; Clínica de Radioterapia de Santa Maria, RS, Brazil., de Mattos MD; Barretos Cancer Hospital., Morais DCR; Latin American Cooperative Oncology Group (LACOG), Brazil.; Oncoclinicas Recife and Hospital Santa Águeda, Brazil., de Castro DG; Latin American Cooperative Oncology Group (LACOG), Brazil.; Department of Radiation Oncology, A.C. Camargo Cancer Center, Brazil., Dal Pra A; Latin American Cooperative Oncology Group (LACOG), Brazil.; Department of Radiation Oncology, University of Miami Miller School of Medicine, United States., Amêndola BE; Innovative Cancer Institute, South Miami, United States., Barros JM; Latin American Cooperative Oncology Group (LACOG), Brazil.; Departamento de Radio-Oncología, Instituto Oncológico Nacional 'Dr. Juan Tanca Marengo'.; Centro de Radioterapia del Hospital Universitario Austral, Argentina., Lara TM; Department of Hematology Oncology, school of Medicine, Pontificia Universidad Catolica de Chile, Chile., Isa N; Clinica IRAM, Santiago de Chile, Chile., de la Mata Moya D; Latin American Cooperative Oncology Group (LACOG), Brazil.; Cancer Center - ABC Medical Center, Mexico., Hidalgo I; Centro Javeriano de Oncología - Hospital Universitario San Ignacio, Colombia., Velilla DG; Instituto Nacional del Cáncer INCAN Paraguay.; Centro Oncológico Revita., Loayza LEA; Oncoservice, Bolivia.; Sociedad Boliviana de Cancerologia Filial La Paz, Bolivia., Montenegro FG; Radiation Oncology Department- Instituto Oncológico Nacional de Panamá, Panama., Sanchez Chacin NO; Radiation therapy Service, Instituto Medico San Nicolas, Aruba., Werutsky G; Latin American Cooperative Oncology Group (LACOG), Brazil., Viani GA; Latin American Cooperative Oncology Group (LACOG), Brazil.; Ribeirão Preto Medical School, Department of Medical Imagings, Hematology and Oncology of University of São Paulo (FMRP-USP), Brazil.
Jazyk:	angličtina
Zdroj:	Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology [Rep Pract Oncol Radiother] 2023 Jul 25; Vol. 28 (3), pp. 340-351. Date of Electronic Publication: 2023 Jul 25 (Print Publication: 2023).
DOI:	10.5603/RPOR.a2023.0046
Abstrakt:	Background: The safety and effectiveness of moderately hypofractionated post-operative radiation therapy for breast cancer were demonstrated by several trials. This study aimed to evaluate the current patterns of practice and prescription preference about moderately hypofractionated post-operative radiation therapy to assess possible aspects that affect the decision-making process regarding the use of fractionation in breast cancer patients in Latin America and the Caribbean (LAC). We also aimed to identify factors that can restrain the utilization of moderately hypofractionated post-operative radiation therapy for breast cancer. Materials an Methods: Radiation oncologists from LAC were invited to contribute to this study. A 38-question survey was used to evaluate their opinions. Results: A total of 173 radiation oncologists from 13 countries answered the questionnaire. The majority of respondents (84.9%) preferred moderately hypofractionated post-operative radiation therapy as their first choice in cases of whole breast irradiation. Whole breast plus regional nodal irradiation, post-mastectomy (chest wall and regional nodal irradiation) without reconstruction, and post-mastectomy (chest wall and regional node irradiation) with reconstruction hypofractionated post-operative radiation therapy was preferred by 72.2% 71.1%, and 53.7% of respondents, respectively. Breast cancer stage, and flap-based breast reconstruction were the factors associated with absolute contraindications for the use of hypofractionated schedules. Conclusion: Even though moderately hypofractionated post-operative radiation therapy for breast cancer is considered a new standard to the vast majority of the patients, its unrestricted application in clinical practice across LAC still faces reluctance. Competing Interests: Conflict of interest None declared. (© 2023 Greater Poland Cancer Centre.)
Databáze:	MEDLINE
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