Mechanical pump complication after HeartMate 3 implantation.

Autor: Merlo A; Department of Surgery, University of North Carolina at Chapel Hill, 4005 Burnett-Womack, CB #7050, Chapel Hill, NC, 27599-7050, USA. Aurelie.merlo@unchealth.unc.edu., Tasoudis P; Department of Surgery, University of North Carolina at Chapel Hill, 4005 Burnett-Womack, CB #7050, Chapel Hill, NC, 27599-7050, USA., de Oliveira GC; Department of Surgery, University of North Carolina at Chapel Hill, 4005 Burnett-Womack, CB #7050, Chapel Hill, NC, 27599-7050, USA., Ikonomidis JS; Department of Surgery, University of North Carolina at Chapel Hill, 4005 Burnett-Womack, CB #7050, Chapel Hill, NC, 27599-7050, USA., Tessmann P; Department of Surgery, University of North Carolina at Chapel Hill, 4005 Burnett-Womack, CB #7050, Chapel Hill, NC, 27599-7050, USA., Haithcock B; Department of Surgery, University of North Carolina at Chapel Hill, 4005 Burnett-Womack, CB #7050, Chapel Hill, NC, 27599-7050, USA., Caranasos T; Department of Surgery, University of North Carolina at Chapel Hill, 4005 Burnett-Womack, CB #7050, Chapel Hill, NC, 27599-7050, USA.
Jazyk: angličtina
Zdroj: Journal of thrombosis and thrombolysis [J Thromb Thrombolysis] 2024 Jan; Vol. 57 (1), pp. 82-88. Date of Electronic Publication: 2023 Oct 04.
DOI: 10.1007/s11239-023-02892-w
Abstrakt: Background: With the improvement in postoperative complications and long-term survival post LVAD, continuing to improve clinical outcomes will require efforts to decrease long-term complications. The purpose of this study is to describe the incidence of mechanical pump failure requiring surgery, which we define as pump failure secondary to either outflow graft compression, outflow graft obstruction, or pump thrombosis requiring surgical intervention.
Methods: 141 consecutive adult patients who underwent HeartMate3 Implantation using the "cut-then-sew" implantation technique between September 2015 and September 2021 were included in our study. The primary outcome measure was mechanical pump complication (outflow graft obstruction and or pump thrombosis) requiring surgical intervention. Secondary outcome measures included incidence of bleeding, stroke, renal failure, length of stay, and overall survival. Median follow up was 27.3 months.
Results: Eleven (7.8%) of patients developed mechanical pump complications. Six patients developed outflow graft obstruction. Five patients developed acute pump thrombosis. Median time to a mechanical complication was 828 days. Of the 11 patients who underwent surgery, 10 patients (90%) survived to discharge. Overall survival at 1, 3, and 5 years was 82.9%, 69.1% and 55.2% respectively for the entire cohort.
Conclusion: The mechanical pump complication rate of 7.8% which is quite high may be related to duration of follow up, as the median time to mechanical complication was 828 days. This study highlights an important late complication that occurs post LVAD implantation.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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