Prevalence of fibromyalgia in a Brazilian series of patients with multiple sclerosis.
| Autor: | Thomas C; Hospital São Vicente de Paulo, Passo Fundo RS, Brazil., Schneider BT; Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil., Verza CS; Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil., Fassina G; Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil., Weber LR; Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil., Moreira M; Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil., Fusinato PT; Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil., Forcelini CM; Hospital São Vicente de Paulo, Passo Fundo RS, Brazil.; Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo RS, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2023 Sep; Vol. 81 (9), pp. 803-808. Date of Electronic Publication: 2023 Oct 04. |
| DOI: | 10.1055/s-0043-1772673 |
| Abstrakt: | Background: The prevalence of pain in patients with multiple sclerosis is remarkable. Fibromyalgia has been considered as one of the forms of chronic pain encompassed in multiple sclerosis, but data are restricted to studies from Europe and North America. Objective: To assess the prevalence of fibromyalgia in a series of Brazilian patients with multiple sclerosis and the characteristics of this comorbidity. Methods: The present cross-sectional study included 60 consecutive adult patients with multiple sclerosis. Upon consent, participants underwent a thorough evaluation for disability, fatigue, quality of life, presence of fibromyalgia, depression, and anxiety. Results: The prevalence of fibromyalgia was 11.7%, a figure similar to that observed in previous studies. Patients with the comorbidity exhibited worse scores on fatigue (median and interquartile range [IQR]: 68 [48-70] versus 39 [16.5-49]; p < 0.001), quality of life (mean ± standard deviation [SD]: 96.5 ± 35.9 versus 124.8 ± 28.8; p = 0.021), anxiety (mean ± SD: 22.7 ± 15.1 versus 13.8 ± 8.4; p = 0.021), and depression (median and IQR: 23 [6-28] versus 6 [3-12.5]; p = 0.034) indices than patients without fibromyalgia. There was a strong positive correlation between depression and anxiety scores with fatigue (r = 0.773 and r = 0.773, respectively; p < 0.001). Conversely, a moderate negative correlation appeared between the Expanded Disability Status Scale (EDSS), fatigue, and depression scores with quality of life (r= -0.587, r= -0.551, r= -0.502, respectively; p < 0.001). Conclusion: Fibromyalgia is a comorbidity of multiple sclerosis that can enhance fatigue and decrease quality of life, although depression, anxiety, and disability are factors that can potentiate the impact of the comorbidity. Competing Interests: The authors have no conflict of interest to declare. (Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/).) |
| Databáze: | MEDLINE |
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