High Propensity to Switch to Long-acting Injectable HIV PrEP with Cabotegravir in a Cohort of Oral PrEP Experienced Men who Have Sex with Men in Italy.

Autor: Raccagni AR; Vita-Salute San Raffaele University, Via Stamira D'Ancona 20, Milano, 20127, Italy. raccagni.angelo@hsr.it., Galli L; Infectious Diseases Unit, San Raffaele Scientific Institute, Milan, Italy., Lucente MF; Vita-Salute San Raffaele University, Via Stamira D'Ancona 20, Milano, 20127, Italy., Candela C; Vita-Salute San Raffaele University, Via Stamira D'Ancona 20, Milano, 20127, Italy., Lolatto R; Infectious Diseases Unit, San Raffaele Scientific Institute, Milan, Italy., Trentacapilli B; Vita-Salute San Raffaele University, Via Stamira D'Ancona 20, Milano, 20127, Italy., Ponta G; Vita-Salute San Raffaele University, Via Stamira D'Ancona 20, Milano, 20127, Italy., Messina E; Infectious Diseases Unit, San Raffaele Scientific Institute, Milan, Italy., Gianotti N; Infectious Diseases Unit, San Raffaele Scientific Institute, Milan, Italy., Castagna A; Vita-Salute San Raffaele University, Via Stamira D'Ancona 20, Milano, 20127, Italy.; Infectious Diseases Unit, San Raffaele Scientific Institute, Milan, Italy., Nozza S; Vita-Salute San Raffaele University, Via Stamira D'Ancona 20, Milano, 20127, Italy.; Infectious Diseases Unit, San Raffaele Scientific Institute, Milan, Italy.
Jazyk: angličtina
Zdroj: AIDS and behavior [AIDS Behav] 2024 Mar; Vol. 28 (3), pp. 907-911. Date of Electronic Publication: 2023 Oct 04.
DOI: 10.1007/s10461-023-04197-8
Abstrakt: Aim was to investigate the propensity to switch to long-acting injectable HIV pre-exposure prophylaxis (PrEP) with cabotegravir among oral PrEP-experienced men who have sex with men. Out of 377 PrEP users, 325 (86.2%) were interested (would like = 210) or considering (would consider = 115) switch to long-acting PrEP. At multivariable analysis, the odds ratio of interest in long-acting PrEP in non-adherent vs. adherent individuals to oral PrEP was 5.03 (95%CI = 1.73-14.61,p = 0.003) and of consideration 1.63 (95%CI = 0.51-5.23,p = 0.410). We observed very high propensity to switch to long-acting PrEP, particularly among non-adherent users. Rapid availability of long-acting PrEP might address unmet needs of PrEP users in Italy.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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