Metastatic Plasmacytoid Urothelial Carcinoma Masquerading as a Primary Signet Ring Cell Carcinoma of the Duodenum.
| Autor: | Mir AS; Gastroenterology, Virginia Tech Carilion School of Medicine, Roanoke, USA., Mouchli M; Gastroenterology and Hepatology, Cleveland Clinic Foundation, Cleveland, USA., Lebel DP; Pathology, Dominion Pathology Associates, Roanoke, USA.; Basic Science Education, Virginia Tech Carilion School of Medicine, Roanoke, USA., Grider D; Pathology, Carilion Roanoke Memorial Hospital, Roanoke, USA.; Basic Science Education, Virginia Tech Carilion School of Medicine, Roanoke, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Aug 31; Vol. 15 (8), pp. e44454. Date of Electronic Publication: 2023 Aug 31 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.44454 |
| Abstrakt: | Plasmacytoid urothelial carcinoma can histologically mimic gastrointestinal signet ring cell carcinoma, a potential diagnostic pitfall resulting in improper clinical management. We present a rare case of a malignant duodenal ulcer due to metastasis from plasmacytoid urothelial carcinoma. Only by histological and retrospective immunohistochemical comparison with the primary bladder tumor was this revealed as a metastasis from a plasmacytoid urothelial carcinoma. This case report highlights the importance of clinical correlation and comparison with any previous pathology specimens, the limitations of immunohistochemical staining, and the utilization of both old and new immunohistochemical tools when differentiating signet ring cell carcinomas of primary sites versus potential metastases. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Mir et al.) |
| Databáze: | MEDLINE |
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