A Rare Case of Apixaban-Induced Subdural Hematoma in Elderly Heart Failure Patient.

Autor: Abdirahman Ahmed S; Department of Cardiology at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia., Hassan MO; Department of Cardiology at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia., Abdi IA; Department of Cardiology at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia., Mohamud MA; Department of Cardiology at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia., Waberi MM; Department of Cardiology at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia., Elmi Abdi A; Department of Cardiology at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia., Hassan Fujeyra AM; Dean College of Medicine and Health Science at Abrar University, Mogadishu, Somalia., Ali AA; Cardiovascular Surgery Department at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia., Sheikh Hassan M; 4 Neurology Department at Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia.
Jazyk: angličtina
Zdroj: International medical case reports journal [Int Med Case Rep J] 2023 Sep 28; Vol. 16, pp. 623-626. Date of Electronic Publication: 2023 Sep 28 (Print Publication: 2023).
DOI: 10.2147/IMCRJ.S432794
Abstrakt: New oral anticoagulants (NOACs) have become more popular in the last few decades. Although apixaban has been proven to be safer than warfarin and causes less hemorrhage in comparison to other NOACs, it still poses a risk of spontaneous bleeding. We present here an 81-year-old male known case of heart failure with reduced ejection fraction (HFrEF) associated with an apical thrombus of 0.93×1.29 cm who presents with cognitive decline, slurred speech, and right side weakness following apixaban use for his apical thrombus. On further evaluation of non-contrast brain computerized tomography ( CT ), there was a large extra-axial subacute subdural hematoma with thick septations in the left parietal region, measuring 2.6 cm in thickness, causing an a mass effect, and an a midline shift of 1 mm. Following neurosurgery, cardiology, and anesthesiology discussions, the surgery was deferred due to his age and coexisting conditions with regular follow-ups. The patient has now gained full consciousness and is currently undergoing physiotherapy. This case highlights an elderly patient with apixaban-induced subdural hemorrhage, which is a rare entity in the medical literature. Although apixaban is safer than other NOACs, it may cause subdural hemorrhage.
Competing Interests: The authors declare no conflicts of interest in this work.
(© 2023 Abdirahman Ahmed et al.)
Databáze: MEDLINE