Sleep disturbances in women with early-onset menopausal transition: a population-based study.
| Autor: | Salin SAE, Savukoski SM, Pesonen PRO; Northern Finland Birth Cohort, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland., Auvinen JP, Niinimäki MJ |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Menopause (New York, N.Y.) [Menopause] 2023 Nov 01; Vol. 30 (11), pp. 1106-1113. Date of Electronic Publication: 2023 Oct 02. |
| DOI: | 10.1097/GME.0000000000002258 |
| Abstrakt: | Objective: The aim of this study was to investigate sleep disturbances in 46-yr-old women and their association with early-onset menopausal transition. Methods: The women of this cross-sectional birth cohort study were divided into climacteric (n = 359) and preclimacteric (n = 2,302) groups by their menopausal status, defined by follicle-stimulating hormone levels and menstrual history. Sleep disturbances were evaluated with Athens Insomnia Scale 5. We performed univariable and multivariable logistic regression models in which sleep parameters were dependent variables and climacteric status, hot flashes, smoking, and education level were independent variables. The use of hormone therapy was also evaluated in women suffering from sleeping disturbances. Results: On the basis of the scale questions, climacteric women experienced significantly delayed sleep induction (12.2% vs 8.7%, P = 0.047), more problems with awakenings during the night (23.4% vs 14.6%, P < 0.001), earlier final awakening (13.8% vs 9.9%, P = 0.039), and more unsatisfying sleep quality (11.9% vs 7.9%, P = 0.023). Climacteric women who were experiencing hot flashes reported unsatisfactory sleep quality more frequently compared with climacteric women who did not experience hot flashes (17.0% vs 9.2%, P = 0.047). In the univariable and multivariable logistic regression models, being climacteric was independently associated with different impaired sleeping parameters. Most climacteric women who had a scale score of 4 or greater were not using hormone therapy, according to their medicine purchases over the past year. Conclusions: Being climacteric was associated with sleep disturbances in women in their mid-40s. However, this association seemed to be particularly driven by hot flashes. Most climacteric women with clinically significant sleeping disturbances were not using hormone therapy. Competing Interests: Financial disclosure/conflicts of interest: S.M.S. received a past grant from the Finnish Medical Foundation, a past grant from the Finnish Menopause Society, and a past grant from the Juho Vainio Foundation. The other authors have nothing to disclose. (Copyright © 2023 by The Menopause Society.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|