Efficacy of Sacral Nerve Stimulation in Non-constipated Irritable Bowel Syndrome Patients: A Systematic Review.

Autor: Garcia-Cabrera AM; Virgen del Rocío University Hospital, Seville, Spain. anam.gcabrera@gmail.com., De la Portilla F; Virgen del Rocío University Hospital, Seville, Spain. delaportilla@ucpsevilla.es., Jiménez-Rodríguez RM; Virgen del Rocío University Hospital, Seville, Spain. ros_j_r@hotmail.com., Vázquez-Monchul JM; Virgen del Rocío University Hospital, Seville, Spain. jmvmco@hotmail.com., Reyes-Díaz ML; Virgen del Rocío University Hospital, Seville, Spain. milu_1983@hotmail.com., Ramallo-Solís IM; Virgen del Rocío University Hospital, Seville, Spain. irene.ramallo@gmail.com., Pintor-Tortolero J; Virgen del Rocío University Hospital, Seville, Spain. jose.pintor.tortolero@gmail.com., Dios-Barbeito S; Virgen del Rocío University Hospital, Seville, Spain. sandra_dios89@hotmail.com., Padillo-Ruiz FJ; Virgen del Rocío University Hospital, Seville, Spain. javierpadilloruiz@gmail.com.
Jazyk: angličtina
Zdroj: Journal of gastrointestinal and liver diseases : JGLD [J Gastrointestin Liver Dis] 2023 Sep 29; Vol. 32 (3), pp. 384-392. Date of Electronic Publication: 2023 Sep 29.
DOI: 10.15403/jgld-4801
Abstrakt: Background and Aims: Irritable bowel syndrome (IBS) is a prevalent disorder with a complex and heterogeneous physiopathology, including a dysregulation of gut-brain axis. Treatment for IBS is targeted to the predominant symptom and requires a multidisciplinary approach. This review aims to evaluate the efficacy and safety of sacral nerve stimulation in non-constipated IBS patients Methods: A literature search was carried out on MEDLINE, The Cochrane Central Register of Controlled Trials (CENTRAL) and Web of Science databases for all relevant articles. Quality of included papers was assessed using standardized guidelines Results: Of 129 initial citations, 7 articles met our predefined inclusion criteria, including five randomized trials, a pilot study and a descriptive follow-up study. Five of 7 studies reported a positive effect of sacral nerve stimulation on symptoms and quality of life improvement in non-constipated IBS patients. No study reported serious adverse events.
Conclusions: Despite initial promising results of sacral nerve stimulation in non-constipated IBS patients, studies with larger sample sizes and longer follow-up are required.
Databáze: MEDLINE