Association between dietary factors, symptoms, and psychological factors in adults with dyspepsia: A cross-sectional study.

Autor: Cooke ZM; Department of Food, Nutrition and Dietetics, La Trobe University, Bundoora, Victoria, Australia., Resciniti SM; Department of Food, Nutrition and Dietetics, La Trobe University, Bundoora, Victoria, Australia., Wright BJ; Department of Psychology, Counselling, and Therapy, La Trobe University, Bundoora, Victoria, Australia., Hale MW; Department of Psychology, Counselling, and Therapy, La Trobe University, Bundoora, Victoria, Australia., Yao CK; Department of Gastroenterology, Monash University, Alfred Health, Melbourne, Victoria, Australia., Tuck CJ; Department of Food, Nutrition and Dietetics, La Trobe University, Bundoora, Victoria, Australia.; Department of Nursing and Allied Health, Swinburne University, Hawthorn, Victoria, Australia., Biesiekierski JR; Department of Food, Nutrition and Dietetics, La Trobe University, Bundoora, Victoria, Australia.; Department of Nutrition, Dietetics & Food, Monash University, Notting Hill, Victoria, Australia.
Jazyk: angličtina
Zdroj: Neurogastroenterology and motility [Neurogastroenterol Motil] 2023 Dec; Vol. 35 (12), pp. e14684. Date of Electronic Publication: 2023 Sep 28.
DOI: 10.1111/nmo.14684
Abstrakt: Background: Evidence-based dietary management approaches for symptoms of dyspepsia are lacking. This study aimed to compare dietary factors, symptoms, quality of life (QOL) and salivary cortisol in dyspepsia participants and healthy controls.
Methods: A cross-sectional survey was completed by adults with dyspepsia (n = 121) meeting Rome IV criteria and healthy controls (n = 52). Outcome measures included self-reported questionnaires about dietary habits, triggers, restrictions, dietary management approaches, nutritional intake, psychological variables, QOL, gastrointestinal symptoms, and optional cortisol awakening response (CAR) via saliva samples. Data were analyzed using Chi-square or Mann-Whitney U. Cortisol awakening response data was analyzed using moderated regression controlling for age, gender and distress.
Key Results: Fermentable carbohydrates (FODMAPs) (55%) were the most reported trigger in adults with dyspepsia. The dyspepsia group (88%) followed special diets more than controls (47%; p < 0.001), with a low FODMAP diet being most common (69%). The dyspepsia group consumed less fiber (p = 0.014), calcium (p = 0.015), and total FODMAPs (p < 0.001) than controls. There was a greater prevalence of comorbid anxiety (41%) and depression (31%) in dyspepsia compared to controls (15% and 12%, respectively, p < 0.001 and p = 0.006). The dyspepsia group had poorer QOL and greater gastrointestinal symptom severity than controls (p < 0.001). There was a negative association between anxiety and CAR (p = 0.001) in dyspepsia but not in controls.
Conclusions & Inferences: Adults with dyspepsia follow special diets more than controls and perceive FODMAPs as a key dietary trigger. These findings highlight the importance of monitoring nutritional adequacy and QOL, and emphasize mechanisms of depleted stress response in dyspepsia, warranting further exploration.
(© 2023 The Authors. Neurogastroenterology & Motility published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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