Longitudinal radiological follow-up of individual level non-ischemic cerebral enhancing lesions following endovascular aneurysm treatment.

Autor:	Guetarni Z; Department of Interventional Neuroradiology, Pitié-Salpêtrière Hospital, Paris, France., Bernard R; Department of Neurosurgical Anesthesiology and Intensive Care, Pitié-Salpêtrière Hospital, Paris, France., Boulouis G; Department of Interventional Neuroradiology, CHU de Tours, Tours, France., Labeyrie MA; Department of Interventional Neuroradiology, Hopital Lariboisiere, Paris, France., Biondi A; Department of Interventional Neuroradiology, Besançon University Hospital, Besancon, France., Velasco S; Department of Interventional Neuroradiology, CHU de Poitiers, Poitiers, France., Saliou G; Department of Diagnostic and Interventional Radiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Vaud, Switzerland., Bartolini B; Department of Diagnostic and Interventional Radiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Vaud, Switzerland., Daumas-Duport B; Department of Interventional Neuroradiology, University Hospital of Nantes, Nantes, France., Bourcier R; Department of Interventional Neuroradiology, University Hospital of Nantes, Nantes, France., Janot K; Department of Interventional Neuroradiology, CHU de Tours, Tours, France., Herbreteau D; Department of Interventional Neuroradiology, CHU de Tours, Tours, France., Michelozzi C; Department of Interventional Neuroradiology, Michallon Hospital, La Tronche, France., Premat K; Department of Interventional Neuroradiology, Pitié-Salpêtrière Hospital, Paris, France., Redjem H; Department of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France., Escalard S; Department of Interventional Neuroradiology, Fondation Rothschild Hospital, Paris, France., Bricout N; Department of interventional Neuroradiology, Centre Hospitalier Universitaire de Lille, Lille, France., Thouant P; Department of Neuroradiology, F Mitterand Hospital, Dijon, France., Arteaga C; Radiology Department, Hôpital d'Instruction des Armées Sainte-Anne Bibliothèque, Toulon, Provence-Alpes-Côte d'Azu, France., Pierot L; Department of Interventional Neuroradiology, University Hospital Reims, Reims, France., Tahon F; Department of Neuroradiology, Grenoble Alpes University Hospital, Grenoble, France., Boubagra K; Department of Neuroradiology, Grenoble Alpes University Hospital, Grenoble, France., Ikka L; Department of Interventional Neuroradiology, Bicetre Hospital, Le Kremlin Bicetre, France., Chabert E; Department of Neuroradiology, Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, France., Lenck S; Department of Interventional Neuroradiology, Pitié-Salpêtrière Hospital, Paris, France., Guédon A; Department of Interventional Neuroradiology, Hopital Lariboisiere, Paris, France., Consoli A; Diagnostic and Therapeutic Neuroradiology Department, Hopital Foch, Suresnes, Île-de-France, France., Saleme S; Department of Interventional Neuroradiology, Centre Hospitalier Universitaire de Limoges, Limoges, France., Forestier G; Department of Interventional Neuroradiology, Centre Hospitalier Universitaire de Limoges, Limoges, France., Di Maria F; Diagnostic and Therapeutic Neuroradiology Department, Hopital Foch, Suresnes, Île-de-France, France., Ferré JC; Department of Neuroradiology, University Hospital of Rennes, Rennes, France., Anxionnat R; Department of Diagnostic and Interventional Neuroradiology, CHRU Nancy, Nancy, Lorraine, France., Eugene F; Department of Neuroradiology, University Hospital of Rennes, Rennes, France., Kerleroux B; Department of Interventional Neuroradiology, Saint Anne Hospital Centre, Paris, France., Dargazanli C; Department of Neuroradiology, University Hospital Centre Montpellier, Montpellier, Occitanie, France., Sourour NA; Department of Interventional Neuroradiology, Pitié-Salpêtrière Hospital, Paris, France., Clarençon F; Department of Interventional Neuroradiology, Pitié-Salpêtrière Hospital, Paris, France., Shotar E; Department of Interventional Neuroradiology, Pitié-Salpêtrière Hospital, Paris, France eimad.shotar@aphp.fr.
Jazyk:	angličtina
Zdroj:	Journal of neurointerventional surgery [J Neurointerv Surg] 2024 Jul 16; Vol. 16 (8), pp. 838-845. Date of Electronic Publication: 2024 Jul 16.
DOI:	10.1136/jnis-2023-020060
Abstrakt:	Background: Non-ischemic cerebral enhancing (NICE) lesions following aneurysm endovascular therapy are exceptionally rare, with unknown longitudinal evolution. Objective: To evaluate the radiological behavior of individual NICE lesions over time. Methods: Patients included in a retrospective national multicentric inception cohort were analyzed. NICE lesions were defined, using MRI, as delayed onset punctate, nodular, or annular foci enhancements with peri-lesion edema, distributed in the vascular territory of the aneurysm treatment, with no other confounding disease. Lesion burden and the longitudinal behavior of individual lesions were assessed. Results: Twenty-two patients were included, with a median initial lesion burden of 36 (IQR 17-54) on the first MRI scan. Of the 22 patients with at least one follow-up MRI scan, 16 (73%) had new lesions occurring mainly within the first 200 weeks after the date of the procedure. The median number of new lesions per MRI was 6 (IQR 2-16). Among the same 22 patients, 7 (32%) had recurrent lesions. The median persistent enhancement of a NICE lesion was 13 weeks (IQR 6-30). No factor was predictive of early regression of enhancement activity with lesion regression kinetics mainly being patient-dependent. Conclusions: The behavior of individual NICE lesions was found to be highly variable with an overall patient-dependent regression velocity. Competing Interests: Competing interests: FC reports conflict of interest with Medtronic, Guerbet, Balt Extrusion (payment for readings), Codman Neurovascular (core laboratory). N-AS is consultant for Medtronic, Balt Extrusion, Microvention; stock/stock options: Medina. The other authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper. The manuscript is not supported by industry. (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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