Association of Serotonin Receptor Gene Polymorphisms with Regulatory and Adaptive Capacities of Medical Students.

Autor: Kashina YV; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia. yulia-kashina@yandex.ru., Cherednik IL; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia., Pokrovsky VM; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia., Polishchuk SV; Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2023 Aug; Vol. 175 (4), pp. 424-426. Date of Electronic Publication: 2023 Sep 28.
DOI: 10.1007/s10517-023-05878-z
Abstrakt: Molecular genetic analysis of polymorphic variants of serotonin receptor genes (HTR2C and HTR2A) was performed in 89 healthy medical students and regulatory and adaptive capacities were determined by cardiorespiratory synchronism. The relationship of serotonin receptor gene polymorphisms and the regulatory and adaptive capabilities of the body were revealed. The highly active *G allele and *G/*G genotype of the serotonin receptor HTR2C gene and the heterozygous *A/*G genotype of the serotonin receptor HTR2A gene are associated with "good" regulatory and adaptive capacities. The low-active *C allele of the serotonin receptor HTR2C gene is associated with "low" regulatory and adaptive capacities.
(© 2023. Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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