Coenzyme Q10 Supplementation in Athletes: A Systematic Review.

Autor: Fernandes MSS; Graduate Program in Neuropsychiatry and Behavioral Sciences, Center for Medical Sciences, Federal University of Pernambuco, Recife 50740-600, Pernambuco, Brazil.; Programa de Pós-Graduação em Biologia Aplicada à Saúde, Centro de Biociências, Universidade Federal de Pernambuco, Recife 50740-600, Pernambuco, Brazil., Fidelis DEDS; Programa de Pós-Graduação em Biologia Aplicada à Saúde, Centro de Biociências, Universidade Federal de Pernambuco, Recife 50740-600, Pernambuco, Brazil., Aidar FJ; Department of Physical Education, Federal University of Sergipe, São Cristovão 49100-000, Sergipe, Brazil., Badicu G; Department of Physical Education and Special Motricity, Faculty of Physical Education and Mountain Sports, Transilvania University of Braşov, 500068 Braşov, Romania., Greco G; Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Study of Bari, 70124 Bari, Italy., Cataldi S; Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Study of Bari, 70124 Bari, Italy., Santos GCJ; Graduate Program in Nutrition, Federal University of Pernambuco, Recife 50740-600, Pernambuco, Brazil., de Souza RF; Department of Physical Education, Federal University of Sergipe, São Cristovão 49100-000, Sergipe, Brazil., Ardigò LP; Department of Teacher Education, NLA University College, 5812 Oslo, Norway.
Jazyk: angličtina
Zdroj: Nutrients [Nutrients] 2023 Sep 15; Vol. 15 (18). Date of Electronic Publication: 2023 Sep 15.
DOI: 10.3390/nu15183990
Abstrakt: Background: To summarize available evidence in the literature on the impacts of CoQ 10 supplementation on metabolic, biochemical, and performance outcomes in athletes.
Methods: Six databases, Cochrane Library (33 articles), PubMed (90 articles), Scopus (55 articles), Embase (60 articles), SPORTDiscus (1056 articles), and Science Direct (165 articles), were researched. After applying the eligibility criteria, articles were selected for peer review independently as they were identified by June 2022. The protocol for this systematic review was registered on PROSPERO (CRD42022357750).
Results: Of the 1409 articles found, 16 were selected for this systematic review. After CoQ 10 supplementation, a decrease in oxidative stress markers was observed, followed by higher antioxidant activity. On the other hand, lower levels of liver damage markers (ALT); Aspartate aminotransferase (AST); and Gamma-glutamyl transpeptidase (γGT) were identified. Finally, we found a reduction in fatigue indicators such as Creatine Kinase (CK) and an increase in anaerobic performance.
Conclusions: This systematic review concludes that supplementation with orally administered CoQ 10 (30-300 mg) was able to potentiate plasma antioxidant activity and anaerobic performance, reducing markers linked to oxidative stress and liver damage in athletes from different modalities aged 17 years old and older.
Databáze: MEDLINE
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