Frequent Follow-Up of Delisted Liver Transplant Candidates Is Necessary: An Observational Study about Characteristics and Outcomes of Delisted Liver Transplant Candidates.

Autor: Payani E; Department of General-, Visceral- and Transplant Surgery, LMU University Hospital, 81377 Munich, Germany.; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany., Koliogiannis D; Department of General-, Visceral- and Transplant Surgery, LMU University Hospital, 81377 Munich, Germany.; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany., Schoenberg MB; Faculty of Medicine, LMU University Hospital, 81377 Munich, Germany., Koch D; Department of General-, Visceral- and Transplant Surgery, LMU University Hospital, 81377 Munich, Germany.; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany., Eser-Valeri D; Department of Psychiatry, LMU University Hospital, 81377 Munich, Germany., Denk G; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany.; Department of Medicine II, LMU University Hospital, 81377 Munich, Germany., Rehm M; Department of Anesthesiology, LMU University Hospital, 81377 Munich, Germany., Schäfer S; Department of Anesthesiology, LMU University Hospital, 81377 Munich, Germany.; Department of Anesthesiology, Carl von Ossietzky University Oldenburg, 26121 Oldenburg, Germany., Ehmer U; Department of Medicine II, Technical University (TU) Munich Klinikum Rechts der Isar, 81675 Munich, Germany., Kremer AE; Department of Medicine I, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.; Department of Gastroenterology and Hepatology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland., Meiser B; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany., Werner J; Department of General-, Visceral- and Transplant Surgery, LMU University Hospital, 81377 Munich, Germany.; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany., Guba M; Department of General-, Visceral- and Transplant Surgery, LMU University Hospital, 81377 Munich, Germany.; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany., Börner N; Department of General-, Visceral- and Transplant Surgery, LMU University Hospital, 81377 Munich, Germany.; Transplant Center Munich, LMU University Hospital, 81377 Munich, Germany.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2023 Sep 10; Vol. 12 (18). Date of Electronic Publication: 2023 Sep 10.
DOI: 10.3390/jcm12185880
Abstrakt: This observational study focuses on the characteristics and survival of patients taken off of the liver transplant waiting list. Assessment of post-delisting survival and a frequent follow-up of patients after delisting are important keys to improve the survival rate of patients with liver failure after being delisted. Within this study, delisted liver transplant candidates were divided into the following groups: (1) "too good" (54%) or (2) "too sick" (22%) for transplantation, (3) adherence issues (12%) or (4) therapy goal changed (11%). The 5-year survival after delisting within these groups was 84%, 9%, 50%, and 68%, respectively. Less than 3% of the delisted patients had to be relisted again. The clinical expert decision of the multidisciplinary transplant team was sufficiently accurate to differentiate between patients requiring liver transplantation and those who were delisted after a stable recovery of liver function. The assessment of post-delisting survival may serve as a complementary metric to assess differences in center practices and to estimate cumulative post-delisting mortality risk.
Databáze: MEDLINE
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