Effectiveness of nutritional support to improve treatment adherence in patients with tuberculosis: a systematic review.

Autor: Wagnew F; National Centre for Epidemiology and Population Health, College of Health and Medicine, The Australian National University, Canberra, Australian Capital Territory, Australia.; College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia., Gray D; Population Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Tsheten T; National Centre for Epidemiology and Population Health, College of Health and Medicine, The Australian National University, Canberra, Australian Capital Territory, Australia., Kelly M; National Centre for Epidemiology and Population Health, College of Health and Medicine, The Australian National University, Canberra, Australian Capital Territory, Australia., Clements ACA; Penninsula Medical School, University of Plymouth, Plymouth, United Kingdom., Alene KA; Geospatial and Tuberculosis Research Team, Telethon Kids Institute, Nedlands, Western Australia, Australia.; Faculty of Health Sciences, School of Population Health, Curtin University, Bentley, Western Australia, Australia.
Jazyk: angličtina
Zdroj: Nutrition reviews [Nutr Rev] 2024 Sep 01; Vol. 82 (9), pp. 1216-1225.
DOI: 10.1093/nutrit/nuad120
Abstrakt: Context: Nutritional interventions substantially improve tuberculosis (TB) treatment outcomes and prevent complications. However, there is limited evidence about the connections between having nutritional support and TB treatment adherence.
Objective: The aim of this study was to determine the effectiveness of nutritional support in improving treatment adherence among patients with TB.
Data Sources: Databases, including PubMed, Embase (Ovid), Web of Science, and Scopus, were comprehensively reviewed to identify relevant studies reporting the impacts of nutritional support on TB treatment adherence.
Data Extraction: Two authors independently screened the title, abstracts, and full article texts to identify eligible studies and assess the risk of bias. Observational and interventional studies were included.
Data Analysis: A narrative synthesis approach was used to summarize the findings qualitatively.
Results: From the search, 3059 publications were identified; of these, 8 studies were included in this systematic review. Three types of nutritional interventions were identified: food baskets (eg, energy, micronutrient- or macronutrient-enriched food support), nutritional advice and guidance, and incentives for buying foods. Although 5 studies reported that nutritional support significantly improved treatment adherence in patients with TB, 3 studies showed that nutritional support had no effect on TB treatment adherence.
Conclusions: Providing nutritional support may improve adherence to TB treatment. However, more well-powered, high-quality trials are warranted to demonstrate the effect of nutrition support on cost-effectively improving adherence to TB treatment.
Systematic Review Registration: PROSPERO registration no. CRD42023392162.
(© The Author(s) 2023. Published by Oxford University Press on behalf of the International Life Sciences Institute.)
Databáze: MEDLINE