Progression of choroidal thickness on EDI-OCT as the first sign of Orbital Lymphoma.

Autor:	Ji V; Department of Ophthalmology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain.; Department of Ophthalmology, Institut Condal d'Oftalmologia, Via Augusta 61, 08006 Barcelona, Spain.; Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.; Institut d´Investigació Biomèdica Sant Pau (IIB SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain., M GR; Department of Ophthalmology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain., M GV; Department of Ophthalmology, Queens Hospital, Barking Havering and Redbridge NHS Trust, Rom Valley Way, Romford, United Kingdom RM7 0AG., I LG; Department of Ophthalmology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain., D RL; Department of Ophthalmology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain., P S; Vitreoretinal Department, Moorfields Eye Hospital, London, United Kingdom.
Jazyk:	angličtina
Zdroj:	Retinal cases & brief reports [Retin Cases Brief Rep] 2023 Sep 20. Date of Electronic Publication: 2023 Sep 20.
DOI:	10.1097/ICB.0000000000001497
Abstrakt:	Purpose: To present an orbital extranodal marginal zone B cell lymphoma (MALT lymphoma) with increased choroidal thickness as the first diagnostic sign. Methods: A patient presented with mild blurred vision in the left eye. Progressively increased choroidal thickness was demonstrated by EDI-OCT and ocular ultrasound confirmed diffuse choroidal effusion. Orbital MRI revealed a well-circumscribed intraconal orbital mass surrounding the optic nerve and molding around the globe. An orbital biopsy of the lesion with subsequent histological and immunohistochemical analyses demonstrated MALT lymphoma. Results: After initial treatment with rituximab without improvement, the patient received orbital radiotherapy (36 Gy in 20 sessions). A reduction in choroidal thickness was observed during follow-up visits. Congestion of the choroidal vasculature and choroidal infiltration by the lymphoma are discussed as possible causative mechanisms. Conclusion: EDI-OCT can be a helpful tool to detect the presence of orbital lymphoid tumors in contact with the globe and to monitor response to therapy. Competing Interests: The authors have no conflicts of interests to disclose.
Databáze:	MEDLINE
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