Textural Analysis of the Hyperdense Artery Sign in Patients with Acute Ischemic Stroke Predicts the Outcome of Thrombectomy.

Autor:	Mărginean L; Radiology and Medical Imaging, Clinical Sciences Department, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.; Interventional Radiology Department, Târgu Mureș County Emergency Clinical Hospital, 540136 Targu Mures, Romania., Filep RC; Interventional Radiology Department, Târgu Mureș County Emergency Clinical Hospital, 540136 Targu Mures, Romania., Suciu BA; Department of Anatomy, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania., Jovin TG; Cooper Neurological Institute, Cherry Hill, NJ 08002, USA., Ștefan PA; Anatomy and Embryology, Morphological Sciences Department, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Victor Babeș, 400012 Cluj-Napoca, Romania.; Radiology and Imaging Department, County Emergency Hospital, Clinicilor Street, Number 3-5, 400006 Cluj-Napoca, Romania., Lupean RA; Histology, Morphological Sciences Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, Louis Pasteur Street, Number 4, 400349 Cluj-Napoca, Romania., Arbănași EM; Faculty of Pharmacy, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania., Arbănași EM; Clinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.; Center for Advanced Medical and Pharmaceutical Research, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania., Opriș DR; Emergency Institute for Cardiovascular Diseases and Transplantation (IUBCVT) of Târgu Mureș, 540136 Targu Mures, Romania., Timm AN; Department of Anatomy, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania., Vodă R; Department of Anatomy, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania., Vunvulea V; Department of Anatomy, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania.; Radiology and Medical Imaging Laboratory, Târgu Mureș County Emergency Clinical Hospital, 540136 Targu Mures, Romania.
Jazyk:	angličtina
Zdroj:	Journal of cardiovascular development and disease [J Cardiovasc Dev Dis] 2023 Aug 24; Vol. 10 (9). Date of Electronic Publication: 2023 Aug 24.
DOI:	10.3390/jcdd10090359
Abstrakt:	Textural analysis is pivotal in augmenting the diagnosis and outcomes of endovascular procedures for stroke patients. Due to the detection of changes imperceptible to the human eye, this type of analysis can potentially aid in deciding the optimal type of endovascular treatment. We included 40 patients who suffered from acute ischemic stroke caused by large vessel occlusion, and calculated 130 different textural features based on the non-enhanced CT scan using an open-source software (3D Slicer). Using chi-squared and Mann-Whitney tests and receiver operating characteristics analysis, we identified a total of 21 different textural parameters capable of predicting the outcome of thrombectomy (quantified as the mTICI score), with variable sensitivity (50-97.9%) and specificity (64.6-99.4%) rates. In conclusion, CT-based radiomics features are potential factors that can predict the outcome of thrombectomy in patients suffering from acute ischemic stroke, aiding in the decision between aspiration, mechanical, or combined thrombectomy procedure.
Databáze:	MEDLINE
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