| Autor: |
Alía Navarro V; Medical Oncology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain., Martínez Delfrade Í; Medical Oncology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain.; Ramón y Cajal Health Research Institute (IRYCIS), 28034 Madrid, Spain., De Frutos González B; Medical Oncology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain.; Ramón y Cajal Health Research Institute (IRYCIS), 28034 Madrid, Spain., Morón García B; Medical Oncology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain.; Ramón y Cajal Health Research Institute (IRYCIS), 28034 Madrid, Spain., Barrill Corpa AM; Medical Oncology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain., Sotoca Rubio P; Medical Oncology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain., Peñas García B; Gastroenterology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain., Ferrer Gómez A; Pathology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain., Perna Monroy C; Pathology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain., Ferreiro Monteagudo R; Medical Oncology Department, Ramón y Cajal University Hospital, 28034 Madrid, Spain.; Ramón y Cajal Health Research Institute (IRYCIS), 28034 Madrid, Spain.; Biomedical Research Network in Cancer (CIBERONC), 28029 Madrid, Spain. |
| Abstrakt: |
Extrapulmonary small-cell carcinoma (SCC) is a rare neoplasm that shares certain features with its pulmonary counterpart and occurs predominantly in the gastrointestinal tract (GIT). It is a high-grade and poorly differentiated neuroendocrine tumor, usually diagnosed in advanced stages, with a poor prognosis and few therapeutic options in that setting. This is a case report of a 77-year-old Spanish male patient with localized SCC of the colon, who presented a pathological complete response in the surgical specimen after neoadjuvant chemotherapy with cisplatin and etoposide. To date, 5 years after surgery, the patient remains without evidence of tumor recurrence. As clinical guidelines for the management of this entity are lacking, and therefore its management has not been standardized, an attempt to summarize the current evidence in the literature was made. |
