Unraveling Monkeypox: An Emerging Threat in Global Health.

Autor: Shehryar A; Internal Medicine, Allama Iqbal Medical College, Lahore, PAK., Halappa Nagaraj R; Surgery, Avalon University School of Medicine, Willemstad, CUW., Kanwal F; Medicine, Chandka Medical College, Larkana, PAK., Reddy SM; Student, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, IND., Grezenko H; Translational Neuroscience, Barrow Neurological Institute, Phoenix, USA., Raut Y; Medicine, Narendra Kumar Prasadrao (NKP) Salve Institute of Medical Sciences, Nagpur, IND., Fareed MU; Department of Surgery, Nishtar Medical University, Multan, PAK., Abdur Rehman; Surgery, Mayo Hospital, Lahore, PAK., Şahin D; Internal Medicine, Psychiatry, Ege University Hospital, İzmir, TUR., Bakht D; Medicine and Surgery, Mayo Hospital, Lahore, PAK., Ramteke P; Medicine, Narendra Kumar Prasadrao (NKP) Salve Institute of Medical Sciences, Nagpur, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Aug 23; Vol. 15 (8), pp. e43961. Date of Electronic Publication: 2023 Aug 23 (Print Publication: 2023).
DOI: 10.7759/cureus.43961
Abstrakt: Monkeypox, a viral zoonotic ailment originating in the Central and West African regions, has escalated into a global health issue of growing concern. The current analysis offers an exhaustive examination of monkeypox, emphasizing its historical progression, etiology, epidemiological patterns, pathophysiological mechanisms, clinical manifestations, diagnostic methodologies, treatment modalities, and preventive strategies. The worldwide discontinuation of smallpox vaccination has contributed to an increased incidence of monkeypox, driven by the expansion of vulnerable host populations. Significant strides in diagnostic procedures, prospective antiviral treatments, and vaccine development exhibit potential in managing this affliction, yet obstacles remain in terms of disease control, prevention, and treatment. Additionally, the international propagation of monkeypox underscores the need for robust public health initiatives and the significant role played by global health institutions in disease containment. Prospective research endeavors should strive to enhance our comprehension of the natural reservoirs of monkeypox and its transmission dynamics, evaluate sustained immune responses to novel vaccines, and investigate the potential impact of One Health strategies. This analysis underscores the pressing necessity for increased research and synchronized global efforts to tackle this emergent infectious malady.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Shehryar et al.)
Databáze: MEDLINE