Nonossifying Fibroma Involving Epiphysis of Long Bone-Case Report and Review of the Literature.

Autor: Serinelli S; Department of Pathology., Enniss BA; Department of Pathology., Damron TA; Department of Orthopedic Surgery., Stock H; Department of Radiology, State University of New York, Upstate Medical University, Syracuse, NY., de la Roza GL; Department of Pathology.
Jazyk: angličtina
Zdroj: Applied immunohistochemistry & molecular morphology : AIMM [Appl Immunohistochem Mol Morphol] 2023 Nov-Dec 01; Vol. 31 (10), pp. 697-700. Date of Electronic Publication: 2023 Sep 25.
DOI: 10.1097/PAI.0000000000001158
Abstrakt: Nonossifying fibroma (NOF) is a common benign bone neoplasm and is usually observed in the first 2 decades of life. Most NOFs occur in the metaphysis of long bones of the lower extremities and migrate toward the diaphysis during skeletal maturation. Epiphyseal involvement by NOF has been rarely reported, with only one case found in the English literature. The authors report the second case of NOF involving the epiphysis of a long bone, the proximal tibia of a 21-year-old woman. Clinicians and pathologists should be aware of the rare possibility of epiphyseal involvement of long bones by this condition. Pathologists should select appropriate immunohistochemistry markers to rule out alternative diagnoses.
Competing Interests: The authors declare no conflict of interest.
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Databáze: MEDLINE