Evolution of CT radiation dose in pediatric patients undergoing hybrid 2-[ 18 F]FDG PET/CT between 2007 and 2021.

Autor:	Skawran S; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Sartoretti T; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Gennari AG; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Schwyzer M; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Sartoretti E; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Treyer V; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Maurer A; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Huellner MW; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland., Waelti S; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland.; Department of Radiology and Nuclear Medicine, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland., Messerli M; Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.; University of Zurich, Zurich, Switzerland.
Jazyk:	angličtina
Zdroj:	The British journal of radiology [Br J Radiol] 2023 Dec; Vol. 96 (1152), pp. 20220482. Date of Electronic Publication: 2023 Oct 24.
DOI:	10.1259/bjr.20220482
Abstrakt:	Objectives: To evaluate the evolution of CT radiation dose in pediatric patients undergoing hybrid 2-[ ¹⁸ F]fluoro-2-deoxy-D-glucose (2-[ ¹⁸ F]FDG) PET/CT between 2007 and 2021. Methods and Materials: Data from all pediatric patients aged 0-18 years who underwent hybrid 2-[ ¹⁸ F]FDG PET/CT of the body between January 2007 and May 2021 were reviewed. Demographic and imaging parameters were collected. A board-certified radiologist reviewed all CT scans and measured image noise in the brain, liver, and adductor muscles. Results: 294 scans from 167 children (72 females (43%); median age: 14 (IQR 10-15) years; BMI: median 17.5 (IQR 15-20.4) kg/m ² ) were included. CT dose index-volume (CTDIvol) and dose length product (DLP) both decreased significantly from 2007 to 2021 (both p < 0.001, Spearman's rho coefficients -0.46 and -0.35, respectively). Specifically, from 2007 to 2009 to 2019-2021 CTDIvol and DLP decreased from 2.94 (2.14-2.99) mGy and 309 (230-371) mGycm, respectively, to 0.855 (0.568-1.11) mGy and 108 (65.6-207) mGycm, respectively. From 2007 to 2021, image noise in the brain and liver remained constant ( p = 0.26 and p = 0.06), while it decreased in the adductor muscles ( p = 0.007). Peak tube voltage selection (in kilovolt, kV) of CT scans shifted from high kV imaging (140 or 120kVp) to low kV imaging (100 or 80kVp) ( p < 0.001) from 2007 to 2021. Conclusion: CT radiation dose in pediatric patients undergoing hybrid 2-[ ¹⁸ F]FDG PET/CT has decreased in recent years equaling approximately one-third of the initial amount. Advances in Knowledge: Over the past 15 years, CT radiation dose decreased considerably in pediatric patients undergoing hybrid imaging, while objective image quality may not have been compromised.
Databáze:	MEDLINE
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