International Liver Transplantation Society Global Census: First Look at Pediatric Liver Transplantation Activity Around the World.

Autor:	Rodriguez-Davalos MI; Liver Transplant Unit, Intermountain Primary Children's Hospital and the Center for Global Surgery, University of Utah, Salt Lake City, UT., Lopez-Verdugo F; Liver Transplant Unit, Intermountain Primary Children's Hospital and the Center for Global Surgery, University of Utah, Salt Lake City, UT.; School of Medicine, Tecnologico de Monterrey, Mexico City, Mexico., Kasahara M; Organ Transplantation Center, National Center for Child Health and Development, Tokyo, Japan., Muiesan P; Liver Unit, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom., Reddy MS; The Institute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, and Bharath Institute of Higher Education and Research, Chennai, India., Flores-Huidobro Martinez A; Liver Transplant Unit, Intermountain Primary Children's Hospital and the Center for Global Surgery, University of Utah, Salt Lake City, UT.; School of Medicine, Universidad Anahuac, Mexico City, Mexico., Xia Q; Department of Liver Surgery and Liver Transplantation, Renji Hospital, Shanghai, People's Republic of China., Hong JC; Division of Transplant Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI., Niemann CU; Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA.; Department of Surgery, University of California San Francisco, San Francisco, CA., Seda-Neto J; Department of Hepatology and Liver Transplantation, Hospital Sirio-Libanes, Sao Paulo, Brazil., Miloh TA; Miami Transplant Institute, University of Miami, Miami, FL., Yi NJ; Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea., Mazariegos GV; Hillman Center for Pediatric Transplantation, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA., Ng VL; Division of Pediatric Gastroenterology, Hepatology and Nutrition, and Transplant and Regenerative Medicine Center, The Hospital for Sick Children (SickKids), University of Toronto, Toronto, Canada., Esquivel CO; Department of Abdominal Transplantation, Stanford University Medical Center, Palo Alto, CA., Lerut J; Institute for Experimental and Clinical Research, Université Catholique Louvain, Brussels, Belgium., Rela M; The Institute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, and Bharath Institute of Higher Education and Research, Chennai, India.; Institute of Liver Studies, King's College Hospital, London, United Kingdom.
Jazyk:	angličtina
Zdroj:	Transplantation [Transplantation] 2023 Oct 01; Vol. 107 (10), pp. 2087-2097. Date of Electronic Publication: 2023 Sep 25.
DOI:	10.1097/TP.0000000000004644
Abstrakt:	Background: Over 16 000 children under the age of 15 died worldwide in 2017 because of liver disease. Pediatric liver transplantation (PLT) is currently the standard of care for these patients. The aim of this study is to describe global PLT activity and identify variations between regions. Methods: A survey was conducted from May 2018 to August 2019 to determine the current state of PLT. Transplant centers were categorized into quintile categories according to the year they performed their first PLT. Countries were classified according to gross national income per capita. Results: One hundred eight programs from 38 countries were included (68% response rate). 10 619 PLTs were performed within the last 5 y. High-income countries performed 4992 (46.4%) PLT, followed by upper-middle- (4704 [44·3%]) and lower-middle (993 [9·4%])-income countries. The most frequently used type of grafts worldwide are living donor grafts. A higher proportion of lower-middle-income countries (68·7%) performed ≥25 living donor liver transplants over the last 5 y compared to high-income countries (36%; P = 0.019). A greater proportion of programs from high-income countries have performed ≥25 whole liver transplants (52.4% versus 6.2%; P = 0.001) and ≥25 split/reduced liver transplants (53.2% versus 6.2%; P < 0.001) compared to lower-middle-income countries. Conclusions: This study represents, to our knowledge, the most geographically comprehensive report on PLT activity and a first step toward global collaboration and data sharing for the greater good of children with liver disease; it is imperative that these centers share the lead in PLT. Competing Interests: The authors declare no funding or conflicts of interest. (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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