Vascular refilling depends on the ratio of blood volume to extracellular volume in hemodialysis patients.
| Autor: | Kron J; KfH Kidney Center Berlin-Köpenick, Berlin, Germany., Broszeit S; DRK Clinics Berlin-Köpenick, Department of Nephrology, Berlin, Germany., Volkenandt J; DRK Clinics Berlin-Köpenick, Department of Nephrology, Berlin, Germany., Leimbach T; KfH Kidney Center Berlin-Köpenick, Berlin, Germany., Kron S; KfH Kidney Center Berlin-Köpenick, Berlin, Germany.; DRK Clinics Berlin-Köpenick, Department of Nephrology, Berlin, Germany. |
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| Jazyk: | angličtina |
| Zdroj: | The International journal of artificial organs [Int J Artif Organs] 2023 Oct-Nov; Vol. 46 (10-11), pp. 581-584. Date of Electronic Publication: 2023 Sep 25. |
| DOI: | 10.1177/03913988231201905 |
| Abstrakt: | The ratio of blood volume to extracellular volume is approximately one to three under physiological conditions and also in stable chronic hemodialysis patients. Recently, it was found that this ratio remains unchanged during hemodialysis despite ultrafiltration. This would signify that the higher the ratio, the lower the refilling and vice versa. To test this hypothesis, treatment data of a previous study were re-analyzed. In 79 stable chronic hemodialysis patients, the refilling fraction was 0.749 ± 0.094. There was a significant negative correlation ( r = -0.412; p < 0.001) between the blood volume to extracellular volume ratio and the refilling fraction. The blood volume to extracellular volume relationship seems to be a significant determinant of vascular refilling: the higher the ratio, the lower the refilling, and vice versa. Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Databáze: | MEDLINE |
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