Factors associated with glycemic control and diabetes complications in a group of Saudi patients with type 2 diabetes.

Autor:	Ewid M; Internal Medicine Department, College of Medicine, Sulaiman Al Rajhi University, Bukairyah, AL-Qassim, Saudi Arabia.; Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Algoblan AS; Diabetes Unit, Oyoon Aljewa Hospital, AL-Qassim, Saudi Arabia., Elzaki EM; KFSH-B Diabetes and Endocrinology Center, Al-Qassim, Saudi Arabia., Muqresh MA; College of Medicine, Sulaiman Al Rajhi University, AL-Qassim, Saudi Arabia., Al Khalifa AR; College of Medicine, Sulaiman Al Rajhi University, AL-Qassim, Saudi Arabia., Alshargabi AM; College of Medicine, Sulaiman Al Rajhi University, AL-Qassim, Saudi Arabia., Alotaibi SA; College of Medicine, Sulaiman Al Rajhi University, AL-Qassim, Saudi Arabia., Alfayez AS; King Abddullah Medical City, Mekkah, Saudi Arabia., Naguib M; Diabetes and Endocrinology Unit, Faculty of Medicine Kasr Al-Ainy Hospital, Cairo University, Cairo, Egypt.
Jazyk:	angličtina
Zdroj:	Medicine [Medicine (Baltimore)] 2023 Sep 22; Vol. 102 (38), pp. e35212.
DOI:	10.1097/MD.0000000000035212
Abstrakt:	Poor glycemic control is a risk factor for micro and macrovascular complications of diabetes. The aim of this study was to assess the prevalence and factors related to suboptimal glycemic control and diabetes complications in a group of patients with type 2 diabetes mellitus (T2DM). This cross-sectional descriptive study conducted in Al Qassim region, Saudi Arabia. Two hundred patients with T2DM were enrolled. Demographic, social, and self-care behavior data were collected. A thorough clinical evaluation was done. Glycated hemoglobin, lipid, and kidney profile results were recorded. Mann-Whitney test was used to compare different groups. For comparing categorical data, Chi-square (χ2) test was performed. Multivariate logistic regression analyses used to detect predictors of poor glycemic control and macrovascular and microvascular complications. The median age of patients was 58 years, and 62% of them were males. Only 22.5% of patients had glycated hemoglobin <7%. Forty-four patients (22%) had evidence of macrovascular complications. Retinopathy, neuropathy, and nephropathy were found in 42.5%, 32.5%, and 12%, respectively. Longer diabetes duration was significantly associated with poor glycemic control (OR = 1.006, P < .005). The age of the patients was independently associated with macrovascular complications (OR = 1.050, P = .029). Hyperlipidemia was significantly associated with neuropathy (OR = 0.229, P = .043) and retinopathy (OR = 12.887, P = .003). Although physical activity was lower in patients with suboptimal glycemic levels (P = .024), cardiovascular disease (P = .030), neuropathy (P < .001), retinopathy (P < .001), and nephropathy (P = .019), multivariate analysis showed that it was only independently associated with neuropathy (OR = 0.614, P = .001). The prevalence of suboptimal glycemic control is high in the studied population. Effective health measures are urgently needed to stop diabetes complications, especially retinopathy and neuropathy. Elderly people with long durations of diabetes, and lower physical activity should be the focus of the interventions. Tailored exercise programs are particularly needed for better diabetes control and for the prevention of complications in patients with T2DM. Competing Interests: The authors have no funding and conflicts of interest to disclose. (Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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