Abnormal Presentation and Challenging Diagnosis of Mediastinal Lymphoma: A Case Report.

Autor: Maqboul I; Department of General Surgery, An-Najah National University Hospital, An-Najah National University, Nablus, PSE., Abatli S; Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, PSE., Shbaita S; Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, PSE., Daraghmeh L; Department of General Surgery, An-Najah National University Hospital, Nablus, PSE., Younis O; Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, PSE., Abu Rass H; Department of Pathology, An-Najah National University Hospital, Nablus, PSE.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Sep 21; Vol. 15 (9), pp. e45668. Date of Electronic Publication: 2023 Sep 21 (Print Publication: 2023).
DOI: 10.7759/cureus.45668
Abstrakt: We describe a rare case of classical Hodgkin lymphoma (HL) in a 20-year-old female patient. She presented to our hospital with chest wall swelling after months of post-chest trauma management. The swelling was initially treated as an infected hematoma, and the patient was referred for surgical evacuation. During the surgery, the swelling was found to be a mass that extended to the mediastinum. A biopsy was taken, which later resulted in the diagnosis of a granular cell tumor (GCT). A decision on surgical resection by video-assisted thoracoscopic surgery (VATS) was taken after discussion with the multidisciplinary team of surgery, cardiothoracic surgery, oncology, pathology, and radiology. During the surgery, a frozen section biopsy was taken, which showed no features of lymphoma or granular cell tumors. The surgery was followed by a midline sternotomy to control the bleeding from an accidentally injured major vessel. The bleeding was controlled, and the mass was dissected and sent for histopathological examination. The histopathology showed nodular classical HL features, and the patient was referred for chemotherapy. In our case, the patient was initially diagnosed with GCT, but with complete resection and an adequate biopsy, the mass was found to be a classical HL. Possible cross-cellularity is questioned, and the possible correlation between the two findings encouraged us to report this case.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Maqboul et al.)
Databáze: MEDLINE