Recent progress in metal assisted multicomponent reactions in organic synthesis.
| Autor: | Sakthivel K; Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology (VIT), Chennai, Tamil Nadu, India., Gana RJ; Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology (VIT), Chennai, Tamil Nadu, India., Shoji T; Graduate School of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan., Takenaga N; Faculty of Pharmacy, Meijo University, Nagoya, Japan., Dohi T; Graduate School of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, Japan., Singh FV; Chemistry Division, School of Advanced Sciences, Vellore Institute of Technology (VIT), Chennai, Tamil Nadu, India. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in chemistry [Front Chem] 2023 Sep 08; Vol. 11, pp. 1217744. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023). |
| DOI: | 10.3389/fchem.2023.1217744 |
| Abstrakt: | To prepare complicated organic molecules, straightforward, sustainable, and clean methodologies are urgently required. Thus, researchers are attempting to develop imaginative approaches. Metal-catalyzed multicomponent reactions (MCRs) offer optimal molecular diversity, high atomic efficiency, and energy savings in a single reaction step. These versatile protocols are often used to synthesize numerous natural compounds, heterocyclic molecules, and medications. Thus far, the majority of metal-catalyzed MCRs under investigation are based on metal catalysts such as copper and palladium; however, current research is focused on developing novel, environmentally friendly catalytic systems. In this regard, this study demonstrates the effectiveness of metal catalysts in MCRs. The aim of this study is to provide an overview of metal catalysts for safe application in MCRs. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Sakthivel, Gana, Shoji, Takenaga, Dohi and Singh.) |
| Databáze: | MEDLINE |
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