| Autor: |
Yamada K; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Yaguchi H; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Ishikawa K; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Tanaka D; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Oshima Y; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Mizushima K; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Uwatoko H; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Shirai S; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Takahashi-Iwata I; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Matsushima M; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan., Tanaka K; Department of Animal Model Development, Brain Research Institute, Niigata University, Japan., Yabe I; Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan. |
| Abstrakt: |
A 74-year-old man experienced diplopia, generalized muscle weakness, and acute respiratory failure. He was diagnosed with Lambert-Eaton myasthenic syndrome (LEMS) and treated with immunotherapy, but no improvement was observed, and additional symptoms, including central apnea and hallucinations, appeared. Subsequent serum and cerebrospinal fluid (CSF) analyses confirmed the presence of GABA B receptor antibodies, indicating the coexistence of autoimmune encephalitis. Although there were no findings of malignancy, it is highly likely that occult small-cell lung carcinoma was present. When atypical symptoms occur in patients with LEMS, it is important to consider the possibility of concomitant autoimmune encephalitis. |
