Vitamin D deficiency and hyperglycemia in male rotating shift workers: A disturbed circadian rhythms influence.

Autor: Santos LZAA; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil., Menezes-Júnior LAA; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil; Post-graduate Program in Health and Nutrition, Nutrition School, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil. Electronic address: luiz.menezes@ufop.edu.br., Freitas SN; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil; Post-graduate Program in Health and Nutrition, Nutrition School, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil., Pimenta FAP; Medical School, Federal University of Minas Gerais, Ouro Preto, Minas Gerais, Brazil., Machado-Coelho GLL; Post-graduate Program in Health and Nutrition, Nutrition School, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil; Medical School, Federal University of Minas Gerais, Ouro Preto, Minas Gerais, Brazil., Oliveira FLP; Statistics Department, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil., Neto RMDN; Medical School, Federal University of Minas Gerais, Ouro Preto, Minas Gerais, Brazil., Turbino-Ribeiro SML; School of Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
Jazyk: angličtina
Zdroj: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2023 Oct; Vol. 57, pp. 258-265. Date of Electronic Publication: 2023 Jul 03.
DOI: 10.1016/j.clnesp.2023.06.031
Abstrakt: Background: Shift work is related to several negative impacts on the health of workers. This study aimed to evaluate the association between vitamin D deficiency (VDD) and hyperglycemia in shift workers.
Methodology: This cross-sectional study included male rotating shift workers in an iron ore extraction company. Participants were classified as VDD when 25(OH)D < 20 ng/mL for a healthy population and 25(OH)D < 30 ng/mL for groups at risk for VDD. Hyperglycemia was classified when fasting glucose ≥100 mg/dL or HbA1c ≥ 5.7%. Data were compared using chi-square analysis with Cramer's V as effect size, and Bonferroni correction. Multivariate logistic regression, from a model of determination, was performed to investigate whether VDD was associated with hyperglycemia.
Results: The study evaluated 1411 workers, most workers were aged 30-39 years (53.2%), and 77.5% self-declared as black, brown, with up to complete high school (71.4%) and working alternate shifts for more than 5 years (76.1%). Regarding glucose and vitamin D, 32.0% and 29.1% of the workers had hyperglycemia and VDD, respectively. In multivariate analysis, controlled for confounding factors, workers with VDD had a 119% increased chance of hyperglycemia (OR: 2.19; IC95%: 1.56-3.08). Furthermore, vitamin D levels in distribution quintiles showed a dose-response gradient in relation to hyperglycemia, where increased vitamin D values were associated with a reduction in the occurrence of hyperglycemia.
Conclusion: Rotating shift workers with vitamin D deficiency are more likely to have hyperglycemia.
(Copyright © 2023 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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