Improving TB control: efficiencies of case-finding interventions in Nigeria.

Autor:	Babayi AP; KNCV Nigeria, Abuja., Odume BB; KNCV Nigeria, Abuja., Ogbudebe CL; KNCV Nigeria, Abuja., Chukwuogo O; KNCV Nigeria, Abuja., Nwokoye N; KNCV Nigeria, Abuja., Dim CC; College of Medicine, University of Nigeria Ituku-Ozalla, Enugu, Nigeria., Useni S; KNCV Nigeria, Abuja., Nongo D; United States Agency for International Development Nigeria, Abuja, Nigeria., Eneogu R; United States Agency for International Development Nigeria, Abuja, Nigeria., Chijioke-Akaniro O; National Tuberculosis, Leprosy and Buruli Ulcer Control Programme, Abuja, Nigeria., Anyaike C; National Tuberculosis, Leprosy and Buruli Ulcer Control Programme, Abuja, Nigeria.
Jazyk:	angličtina
Zdroj:	Public health action [Public Health Action] 2023 Sep 21; Vol. 13 (3), pp. 90-96.
DOI:	10.5588/pha.23.0028
Abstrakt:	Setting: KNCV Nigeria implements seven key TB case-finding interventions. It was critical to evaluate the efficiency of these interventions in terms of TB yield to direct future prioritisation in the country. Objectives: To compare the efficiency of active case-finding (ACF) interventions for TB in Nigeria. Design: Data from the 2020-2022 implementing period were analysed retrospectively. Intervention efficiencies were analysed using the number needed to screen (NNS), the number needed to test (NNT) and the true screen-positive (TSP) rate. Results: Across the interventions, 21,704,669 persons were screened for TB, 1,834,447 (8.5%) were presumed to have TB (7.7% pre-diagnostic drop-out rate) and 122,452 were diagnosed with TB (TSP rate of 7.2%). The average TSP rate of interventions that used both the WHO four-symptom screen (W4SS) and portable digital X-ray (PDX) screening algorithm was significantly higher (22.6%) than those that employed the former alone (7.0%; OR 3.9, 95% CI 3.74-3.98; P < 0.001). The average NNT for interventions with W4SS/PDX screening was 4 (range: 4-5), while that of W4SS-only screening was 14 (range: 11-22). Conclusions: Interventions using the PDX in addition to W4SS for TB screening were more efficient in terms of TB case yield than interventions that used symptom-based TB screening only. (© 2023 The Union.)
Databáze:	MEDLINE
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