The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-Zoonotic Avian Influenza and Mycobacterium tuberculosis .

Autor: Blacksell SD; Mahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Nuffield Department of Medicine Research Building, University of Oxford, Oxford, United Kingdom., Dhawan S; Mahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Kusumoto M; Mahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Le KK; Mahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Summermatter K; Institute for Infectious Diseases, University of Bern, Bern, Switzerland., O'Keefe J; Ministry for Primary Industries, Wellington, New Zealand., Kozlovac J; United States Department of Agriculture, Agricultural Research Service, Beltsville, Maryland, USA., Almuhairi SS; Abu Dhabi Agriculture and Food Safety Authority, Abu Dhabi, United Arab Emirates., Sendow I; Research Center for Veterinary Science, National Research and Innovation Agency, Indonesia., Scheel CM; WHO Collaborating Center for Biosafety and Biosecurity, Office of the Associate Director for Laboratory Science, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Ahumibe A; Nigeria Centre for Disease Control and Prevention, Abuja, Nigeria., Masuku ZM; National Institute for Communicable Diseases of the National Health Laboratory Services, Johannesburg, South Africa., Bennett AM; UK Health Security Agency, London, United Kingdom., Kojima K; Department of Epidemic and Pandemic Preparedness and Prevention, World Health Organization (WHO), Geneva, Switzerland., Harper DR; The Royal Institute of International Affairs, London, United Kingdom., Hamilton K; World Organisation for Animal Health (OIE), Paris, France.
Jazyk: angličtina
Zdroj: Applied biosafety : journal of the American Biological Safety Association [Appl Biosaf] 2023 Sep 01; Vol. 28 (3), pp. 135-151. Date of Electronic Publication: 2023 Sep 12.
DOI: 10.1089/apb.2022.0038
Abstrakt: Introduction: The Biosafety Research Road Map reviewed the scientific literature on a viral respiratory pathogen, avian influenza virus, and a bacterial respiratory pathogen, Mycobacterium tuberculosis. This project aims at identifying gaps in the data required to conduct evidence-based biorisk assessments, as described in Blacksell et al. One significant gap is the need for definitive data on M. tuberculosis sample aerosolization to guide the selection of engineering controls for diagnostic procedures.
Methods: The literature search focused on five areas: routes of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination methods.
Results: The available data regarding biosafety knowledge gaps and existing evidence have been collated and presented in Tables 1 and 2. The guidance sources on the appropriate use of biosafety cabinets for specific procedures with M. tuberculosis require clarification. Detecting vulnerabilities in the biorisk assessment for respiratory pathogens is essential to improve and develop laboratory biosafety in local and national systems.
(© Stuart D. Blacksell et al. 2023; Published by Mary Ann Liebert, Inc.)
Databáze: MEDLINE
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