Chronic Obstructive Pulmonary Disease in Cameroon: Prevalence and Predictors-A Multisetting Community-Based Study.

Autor: Massongo M; Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon., Balkissou AD; Faculty of Medicine and Biomedical Sciences, University of Ngaoundéré, Garoua, Cameroon., Endale Mangamba LM; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.; Laquintinie Hospital, Douala, Cameroon., Poka Mayap V; Jamot Hospital, Yaoundé, Cameroon., Ngah Komo ME; Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.; Jamot Hospital, Yaoundé, Cameroon., Nsounfon AW; Central Hospital of Yaoundé, Yaoundé, Cameroon., Kuaban A; Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.; Jamot Hospital, Yaoundé, Cameroon., Pefura Yone EW; Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.; Jamot Hospital, Yaoundé, Cameroon.
Jazyk: angličtina
Zdroj: Pulmonary medicine [Pulm Med] 2023 Sep 13; Vol. 2023, pp. 1631802. Date of Electronic Publication: 2023 Sep 13 (Print Publication: 2023).
DOI: 10.1155/2023/1631802
Abstrakt: Objective: Little is known concerning chronic obstructive pulmonary disease (COPD) in Sub-Saharan Africa (SSA), where the disease remains underdiagnosed. We aimed to estimate its prevalence in Cameroon and look for its predictors.
Methods: Adults aged 19 years and older were randomly selected in 4 regions of Cameroon to participate in a cross-sectional community-based study. Data were collected in the participant's home or place of work. Spirometry was performed on selected participants. COPD was defined as the postbronchodilator forced expiratory volume in 1 second/forced vital capacity ratio (FEV1/FVC) < lower limit of normal, using the global lung initiative (GLI) equations for Black people. Binomial logistic regression was used to seek COPD-associated factors. The strength of the association was measured using the adjusted odds ratio (aOR).
Results: A total of 5055 participants (median age (25 th -75 th percentile) = 43 (30-56) years, 54.9% of women) were enrolled. COPD prevalence (95% confidence interval (95% CI)) was 2.9% (2.4, 3.3)%. Independent predictors of COPD (aOR (95% CI)) were a high educational level (4.7 (2.0, 11.1)), living in semiurban or rural locality (1.7 (1.4, 3.0)), tobacco smoking (1.7 (1.1, 2.5)), biomass fuel exposure (1.9 (1.1, 3.3)), experience of dyspnea (2.2 (1.4, 3.5)), history of tuberculosis (3.6 (1.9, 6.7)), and history of asthma (6.3 (3.4, 11.6)). Obesity was protective factor (aOR (95%CI) = 0.3 (0.2, 0.5)).
Conclusion: The prevalence of COPD was relatively low. Alternative risk factors such as biomass fuel exposure, history of tuberculosis, and asthma were confirmed as predictors.
Competing Interests: The authors declare no conflict of interest.
(Copyright © 2023 Massongo Massongo et al.)
Databáze: MEDLINE
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