Executive functions and behavioral economic demand for cannabis among young adults: Indirect associations with cannabis consumption and cannabis use disorder.

Autor: Coelho SG; Department of Psychology, York University., Hendershot CS; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill., Aston ER; Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University School of Public Health., Ruocco AC; Department of Psychological Clinical Science, University of Toronto., Quilty LC; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health., Tyndale RF; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health., Wardell JD; Department of Psychology, York University.
Jazyk: angličtina
Zdroj: Experimental and clinical psychopharmacology [Exp Clin Psychopharmacol] 2024 Jun; Vol. 32 (3), pp. 305-315. Date of Electronic Publication: 2023 Sep 21.
DOI: 10.1037/pha0000678
Abstrakt: Behavioral economic demand for cannabis is robustly associated with cannabis consumption and cannabis use disorder (CUD). However, few studies have examined the processes underlying individual differences in the relative valuation of cannabis (i.e., demand). This study examined associations between executive functions and cannabis demand among young adults who use cannabis. We also examined indirect associations of executive functions with cannabis consumption and CUD symptoms through cannabis demand. Young adults ( N = 113; 58.4% female; mean age 22 years) completed a Marijuana Purchase Task. Participants also completed cognitive tasks assessing executive functions (set shifting, inhibitory control, working memory) and semistructured interviews assessing past 90-day cannabis consumption (number of grams used) and number of CUD symptoms. Poorer inhibitory control was significantly associated with greater O max (peak expenditure on cannabis) and greater intensity (cannabis consumption at zero cost). Poorer working memory was significantly associated with lower elasticity (sensitivity of consumption to escalating cost). Lower inhibitory control was indirectly associated with greater cannabis consumption and CUD symptoms through greater O max and intensity, and poorer working memory was indirectly associated with greater cannabis consumption and CUD symptoms through reduced elasticity. This study provides novel evidence that executive functions are associated with individual differences in cannabis demand. Moreover, these results suggest that cannabis demand could be a mechanism linking poorer executive functioning with heavier cannabis use and CUD, which should be confirmed in future longitudinal studies. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
Databáze: MEDLINE