Carcinoid syndrome caused by a pulmonary carcinoid mimics intestinal manifestations of ulcerative colitis: A case report.

Autor:	Reyes CM; Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany., Klein H; Division of Thoracic Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany., Stögbauer F; Institute of Pathology, Technical University of Munich, Munich 81675, Germany., Einwächter H; Department of Internal Medicine II, Technical University of Munich, Munich 81675, Germany., Boxberg M; Institute of Pathology, Technical University of Munich, Munich 81675, Germany., Schirren M; Division of Thoracic Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany., Safi S; Division of Thoracic Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany. seyer.safi@mri.tum.de., Hoffmann H; Division of Thoracic Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich 81675, Germany.
Jazyk:	angličtina
Zdroj:	World journal of gastroenterology [World J Gastroenterol] 2023 Sep 07; Vol. 29 (33), pp. 5014-5019.
DOI:	10.3748/wjg.v29.i33.5014
Abstrakt:	Background: Pulmonary carcinoids are rare, low-grade malignant tumors characterized by neuroendocrine differentiation and relatively indolent clinical behavior. Most cases present as a slow-growing polypoidal mass in the major bronchi leading to hemoptysis and pulmonary infection due to blockage of the distal bronchi. Carcinoid syndrome is a paraneoplastic syndrome caused by the systemic release of vasoactive substances that presents in 5% of patients with neuroendocrine tumors. Due to such nonspecific presentation, most patients are misdiagnosed or diagnosed late and may receive several courses of antibiotics to treat recurrent pneumonia before the tumor is diagnosed. Case Summary: We report the case of a 48-year-old male who presented with cough, dyspnea, a history of recurrent pneumonitis, and therapy-refractory ulcerative colitis that completely subsided after the resection of a pulmonary carcinoid. Conclusion: We report and emphasize pulmonary carcinoid as a differential diagnosis in patients with nonresponding inflammatory bowel diseases and recurrent pneumonia. Competing Interests: Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose. (©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze:	MEDLINE
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