Neuroendocrine carcinoma of the cervix: About a rare case and literature review.

Autor:	El Abbassi I; Department of Gynecology and Obstetrics, University hospital center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, Casablanca, Morocco. Electronic address: imane.mammeri.im@gmail.com., Tanguara SO; Department of Gynecology and Obstetrics, University hospital center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, Casablanca, Morocco., Bencherifi Y; Department of Gynecology and Obstetrics, University hospital center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, Casablanca, Morocco., Ennachit M; Department of Gynecology and Obstetrics, University hospital center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, Casablanca, Morocco., Benhessou M; Department of Gynecology and Obstetrics, University hospital center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, Casablanca, Morocco., El Kerroumi M; Department of Gynecology and Obstetrics, University hospital center Ibn Rochd, Casablanca, Morocco.
Jazyk:	angličtina
Zdroj:	International journal of surgery case reports [Int J Surg Case Rep] 2023 Oct; Vol. 111, pp. 108835. Date of Electronic Publication: 2023 Sep 17.
DOI:	10.1016/j.ijscr.2023.108835
Abstrakt:	Introduction: Neuroendocrine carcinomas of the uterine cervix are rare carcinomas, accounting for only 0.9-1.5 % of cervical tumors. Given their rarity and the absence of randomized trials, the diagnostic and therapeutic management of these tumors is complicated and is essentially modeled on that of pulmonary neuroendocrine tumors. Presentation of Case: We report a new case of large-cell neuroendocrine carcinoma of the uterine cervix, and review the various aspects of this rare entity. Discussion: Neuroendocrine carcinoma is a rare and aggressive malignant tumor, It differs from squamous cell carcinoma in its higher recurrence rate and delayed diagnosis. On the other hand, association with human papillomavirus (HPV) 16 and 18 is a common risk factor for both carcinomas. Conclusion: To improve the survival of patients with large-cell neuroendocrine carcinomas of the uterine cervix, it is imperative to conduct multicenter clinical trials aimed at defining an effective, standardized treatment. Competing Interests: Declaration of competing interest The authors declare having no conflicts of interest in this article. (Copyright © 2023. Published by Elsevier Ltd.)
Databáze:	MEDLINE
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