Evaluation of thyroid functions and obesity in obstructive sleep apnea syndrome.
| Autor: | Duksal F; Konya Beyhekim Research and Training Hospital, Department of Chest Diseases - Konya, Turkey., Eren F; Selcuk University, Faculty of Medicine, Department of Neurology - Konya, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2023 Sep 18; Vol. 69 (9), pp. e20230376. Date of Electronic Publication: 2023 Sep 18 (Print Publication: 2023). |
| DOI: | 10.1590/1806-9282.20230376 |
| Abstrakt: | Objective: Obstructive sleep apnea syndrome is associated with many chronic diseases. Methods: Obesity and thyroid function tests were evaluated retrospectively and cross-sectionally for 782 obstructive sleep apnea syndrome patients. Results: The mean patient age was 49.3±11.5 years, and the majority were obese (67.9%) or overweight (26.6%). The mean age of the patients in Group 2 (moderate/severe obstructive sleep apnea syndrome) was higher than that of Group 1 (simple snoring/mild obstructive sleep apnea syndrome). The rate of severe obstructive sleep apnea syndrome among obese patients (35.2%) was significantly higher than that of normal-weight (11.6%) and overweight (18.3%) patients (p=0.001). The oxygen desaturation index/apnea-hypopnea index and levels of leukocytes and C-reactive protein were significantly higher, while mean/minimum saturation values and hemoglobin, hematocrit, and free triiodothyronine levels were significantly lower among obese patients compared with overweight and normal-weight patients (p=0.001). Leukocytes, C-reactive protein, and apnea-hypopnea index/oxygen desaturation index values were higher, and mean/minimum saturation values were lower in Group 2 than in Group 1. Conclusion: There were relationships between obstructive sleep apnea syndrome severity and body mass index. Obesity could be a critical predisposing factor for sleep disturbances. The prevention and control of obesity is important while being treated for obstructive sleep apnea syndrome. |
| Databáze: | MEDLINE |
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