A Case Report of Guillain-Barré Syndrome In Association with SARS-CoV-2 Vaccination in Malaysia.

Autor:	Sii HL; Department of Medicine, Hospital Sibu, KM 5 1/2, Jalan Ulu Oya, 96000 Sibu, Sarawak, Malaysia., Ng SH; Department of Medicine, Hospital Sibu, KM 5 1/2, Jalan Ulu Oya, 96000 Sibu, Sarawak, Malaysia., Wong VF; Department of Medicine, Hospital Sibu, KM 5 1/2, Jalan Ulu Oya, 96000 Sibu, Sarawak, Malaysia., Law WC; Department of Medicine, Hospital Sibu, KM 5 1/2, Jalan Ulu Oya, 96000 Sibu, Sarawak, Malaysia.
Jazyk:	angličtina
Zdroj:	Acta neurologica Taiwanica [Acta Neurol Taiwan] 2023 Dec 30; Vol. 32(4), pp. 207-211.
Abstrakt:	Purpose: Guillain-Barré Syndrome (GBS) associated with SARS-CoV-2 vaccine administration is very rare. Early recognition of GBS at early stage could prevent extensive nerve damage with potential respiratory and autonomic failure. Case Report: We report a case of paraparetic spectrum of GBS in a 53-year-old lady who presented with rapidly progressive acute flaccid paralysis involving both lower extremities with areflexia eight days after the first dose of Sinovac vaccine for SARS-CoV-2 in Malaysia. Cerebrospinal fluid (CSF) albuminocytological dissociation was seen and nerve conduction study (NCS) revealed sensory neuropathy. The diagnosis of GBS was made based on the Brighton criteria. Patient responded well to intravenous immunoglobulin (IVIG). Conclusion: Though there is currently no convincing evidence of any causation between GBS and SARS- CoV-2 vaccination, clinicians should remain vigilant and consider GBS in the differential diagnosis for patient who presents with weakness with reduced or absent deep tendon reflex after vaccination against SARS-CoV-2.
Databáze:	MEDLINE
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