Effectiveness of Robotic Stereotactic Radiotherapy in Patients Undergoing Re-irradiation: A Review.

Autor:	Mohamed Yoosuf AB; Oncology, King Abdullah International Medical Research Center, Riyadh, SAU.; Oncology/Radiation Oncology, King Abdulaziz Medical City, Riyadh, SAU., Alshehri S; Radiation Oncology, King Abdulaziz Medical City, Riyadh, SAU.; Oncology, King Abdullah International Medical Research Center, Riyadh, SAU., Abdul Aziz MZ; Advanced Management of Liver Malignancies Program, Universiti Sains Malaysia, Advanced Medical and Dental Institute, Penang, MYS., Mansor S; Advanced Management of Liver Malignancies Program, Universiti Sains Malaysia, Advanced Medical and Dental Institute, Penang, MYS.; Nuclear Medicine Unit, Pusat Perubatan Universiti Sains Malaysia, Advanced Medical and Dental Institute, Penang, MYS., Appalanaido GK; Advanced Management of Liver Malignancies Program, Universiti Sains Malaysia, Advanced Medical and Dental Institute, Penang, MYS.; Radiotherapy Unit, Pusat Perubatan Universiti Sains Malaysia, Advanced Medical and Dental Institute, Penang, MYS., Alqathami M; Department of Oncology, Ministry of National Guard, Health Affairs, Riyadh, SAU.; Clinical Research, King Abdullah International Medical Research Center, Riyadh, SAU.; Radiological Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Aug 15; Vol. 15 (8), pp. e43500. Date of Electronic Publication: 2023 Aug 15 (Print Publication: 2023).
DOI:	10.7759/cureus.43500
Abstrakt:	Stereotactic ablative radiotherapy (SABR) is a possible treatment option for patients who develop recurrence within or at the edge of a previously irradiated volume. Robotic stereotactic radiotherapy is the result of technological advances in robotic precision, real-time imaging, non-invasive, highly customizable treatment plan, and delivery with sub-millimeter accuracy. This article reviews the radiobiologic, technical, and clinical aspects of robotic-based SABR re-irradiation for various anatomical sites. An extensive literature search was performed to identify articles on the utilization of robotic stereotactic radiotherapy for patients undergoing re-irradiation. The reported prescription dose and fractionation data along with outcomes such as overall survival, local control rates, and toxicities were qualitatively reviewed. The findings consistently indicate that re-irradiation using robotic SABR provides encouraging survival rates with minimal toxicity in the clinical setting of various anatomical sites delivered using locally non-invasive means where other treatment options are scarce. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Mohamed Yoosuf et al.)
Databáze:	MEDLINE
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