| Autor: |
Long XX; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P. R. China., Zhang S; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P. R. China., Xiang LJ; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P. R. China., Hu RH; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P. R. China., Feng TT; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P. R. China., Zhou Y; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P. R. China., Yin X; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang, P. R. China. |
| Abstrakt: |
Grevillosides R-S ( 1-2 ), two new glucosides of 5-alkylresorcinol derivatives, were isolated from the roots of Ardisia crispa (Thunb.) A. DC. The structures of grevillosides R-S ( 1-2 ) were determined by 1D and 2D NMR, HR-MS, UV, IR experiments and by comparison of their spectroscopic and physical data with literature values. In this paper, grevillosides R-S ( 1-2 ) were tested for their radical-scavenging activity (DPPH and ABTS) and α-glucosidase inhibitory activity in vitro . Grevillosides R-S ( 1-2 ) exhibited weak DPPH radical-scavenging activity with IC 50 values of 72.3 and 485.2 μM, respectively. Grevillosides R-S ( 1-2 ) exhibited no inhibitory activity against α-glucosidase. |
