Gastric (gastrointestinal)-type endometrial adenocarcinoma presenting as a solitary endometrial polyp: a case report and literature review on a novel and potentially aggressive endometrial cancer histotype.

Autor:	Bragantini E; Unit of Surgical Pathology, Santa Chiara Hospital, APSS, Trento., Angelico G; Department of Medical and Surgical Sciences and Advanced Technologies 'G.F. Ingrassia', Anatomic Pathology, University of Catania, Catania, Italy., Disanto MG; Unit of Surgical Pathology, Santa Chiara Hospital, APSS, Trento., Magri E; Radiotherapy Unit, Santa Chiara Hospital, Trento., Maccio L; Unit of Surgical Pathology, Santa Chiara Hospital, APSS, Trento., Barbareschi M; Unit of Surgical Pathology, Santa Chiara Hospital, APSS, Trento.; Centre for Medical Sciences - CISMed, University of Trento.
Jazyk:	angličtina
Zdroj:	Pathologica [Pathologica] 2023 Aug; Vol. 115 (4), pp. 227-231.
DOI:	10.32074/1591-951X-870
Abstrakt:	Gastric-type carcinoma of the endometrium is a rare endometrial cancer histotype, recently introduced in the 2020 WHO classification of the female genital tract tumors. Clinico-pathological features, as well as treatment strategies for this rare histotype, are not fully defined. We herein present an unusual case of endometrial carcinoma with mucinous features arising in a 58-year-old menopausal woman. Morphological features of the present case as well as immunohistochemical profile were consistent with gastrointestinal differentiation. Therefore, after clinical and imaging studies ruled out the possibility of a metastatic origin, a final diagnosis of gastric-type carcinoma of the endometrium was rendered. (Copyright © 2023 Società Italiana di Anatomia Patologica e Citopatologia Diagnostica, Divisione Italiana della International Academy of Pathology.)
Databáze:	MEDLINE
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