Essential and dystonic head tremor: More similarities than differences.

Autor: Hollý P; Department of Neurology and Center of Clinical Neuroscience, Charles University, Kateřinská 30, 128 21, Prague 2, Czech Republic. Electronic address: petr.holly@vfn.cz., Duspivová T; Department of Neurology and Center of Clinical Neuroscience, Charles University, Kateřinská 30, 128 21, Prague 2, Czech Republic; Department of Biomedical Informatics, Czech Technical University in Prague, Nám. Sítná 3105, 272 01, Kladno, Czech Republic. Electronic address: duspiter@fbmi.cvut.cz., Kemlink D; Department of Neurology and Center of Clinical Neuroscience, Charles University, Kateřinská 30, 128 21, Prague 2, Czech Republic. Electronic address: david.kemlink@vfn.cz., Ulmanová O; Department of Neurology and Center of Clinical Neuroscience, Charles University, Kateřinská 30, 128 21, Prague 2, Czech Republic. Electronic address: olga.ulmanova@vfn.cz., Rusz J; Department of Neurology and Center of Clinical Neuroscience, Charles University, Kateřinská 30, 128 21, Prague 2, Czech Republic; Department of Circuit Theory, Czech Technical University in Prague, Technická 2, 160 00, Prague 6, Czech Republic. Electronic address: rusz.mz@gmail.com., Krupička R; Department of Biomedical Informatics, Czech Technical University in Prague, Nám. Sítná 3105, 272 01, Kladno, Czech Republic. Electronic address: krupirad@cvut.cz., Jech R; Department of Neurology and Center of Clinical Neuroscience, Charles University, Kateřinská 30, 128 21, Prague 2, Czech Republic. Electronic address: jech@cesnet.cz., Růžička E; Department of Neurology and Center of Clinical Neuroscience, Charles University, Kateřinská 30, 128 21, Prague 2, Czech Republic. Electronic address: eruzi@lf1.cuni.cz.
Jazyk: angličtina
Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2023 Oct; Vol. 115, pp. 105850. Date of Electronic Publication: 2023 Sep 09.
DOI: 10.1016/j.parkreldis.2023.105850
Abstrakt: Introduction: Head tremor is a common symptom of essential tremor (ET) and cervical dystonia (CD). In clinical practice, it is often difficult to distinguish between these two conditions, especially in cases where head tremor predominates.
Objectives: To investigate which clinical and instrumental methods best differentiate ET and CD in patients with head tremor.
Methods: 65 patients were included, of which 23 were diagnosed with ET and head tremor (HT+), 21 with ET without head tremor (HT-) and 21 with CD and dystonic head tremor. 22 healthy volunteers served as controls. All patients were examined using the rating scales for ET (TETRAS), cervical dystonia (TWSTRS), and ataxia (SARA). The Somatosensory Temporal Discrimination Threshold (STDT) was defined as the shortest interval in which an individual recognizes two tactile stimuli as temporally separated.
Results: TETRAS and SARA scores were higher in the HT+ group compared with HT- and CD, with no significant difference between mild head tremor subscores in HT+ and CD. In most HT+ and CD patients, head tremor disappeared supine. The STDT values were significantly higher in the HT+ group compared with controls.
Conclusion: While TWSTRS contributed to assess dystonia severity, the scales of tremor and ataxia were not helpful in differentiating head tremor syndromes. The cessation of head tremor in the supine position could be related to the overall mild head tremor scores in both groups. Increased SARA scores and STDT values in HT+ patients suggest a possible role of cerebellar involvement and altered somatosensory timing that merit further verification.
Competing Interests: Declaration of competing interest All authors declare that they have no disclosure to any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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