Clinical results after external reinforcement of colorectal anastomosis: a systematic review.

Autor:	Gené-Škrabec C; Department of General Surgery, Hospital Universitari Germans Trias i Pujol, School of Medicine, Universitat Autònoma de Barcelona, Institut de Recerca Germans Trias i Pujol - IGTP, Barcelona, Spain., Cremades M; Department of General Surgery, Hospital Universitari Germans Trias i Pujol, School of Medicine, Universitat Autònoma de Barcelona, Institut de Recerca Germans Trias i Pujol - IGTP, Barcelona, Spain., Fernández-Pujol A; Department of General Surgery, King's College London, London, England., Cortinovis S; Department of General Surgery, ASUGI Cattinara, Università degli studi di Trieste, Trieste, Italy., Corral J; Department of General Surgery, Hospital Universitari Germans Trias i Pujol, School of Medicine, Universitat Autònoma de Barcelona, Institut de Recerca Germans Trias i Pujol - IGTP, Barcelona, Spain., Julián JF; Department of General Surgery, Hospital Universitari Germans Trias i Pujol, School of Medicine, Universitat Autònoma de Barcelona, Institut de Recerca Germans Trias i Pujol - IGTP, Barcelona, Spain., Parés D; Department of General Surgery, Hospital Universitari Germans Trias i Pujol, School of Medicine, Universitat Autònoma de Barcelona, Institut de Recerca Germans Trias i Pujol - IGTP, Barcelona, Spain.
Jazyk:	angličtina
Zdroj:	International journal of surgery (London, England) [Int J Surg] 2023 Dec 01; Vol. 109 (12), pp. 4322-4332. Date of Electronic Publication: 2023 Dec 01.
DOI:	10.1097/JS9.0000000000000747
Abstrakt:	Objective: The aim of this review is to describe and assess the existing methods to cover colorectal anastomoses with biomaterials and their clinical impact in reducing anastomotic leakage (AL). Summary Background Data: The most serious complication in colorectal surgery is AL. Despite improvements in its diagnosis and management, AL remains an unresolved issue. To prevent its appearance and clinical consequences, different external reinforcement techniques with synthetic or biomaterials have been described. Methods: A systematic review search of the available literature until June 2022 was performed, looking for all literature regarding external reinforcement of colonic or colorectal anastomoses. After the review process, a classification of materials was proposed into solid and liquid materials, and an assessment of their clinical impact was performed. The study protocol has been registered at PROSPERO and has been reported in the line with PRISMA and AMSTAR Guidelines 11,12 . Results: Ninety-seven articles that fulfilled inclusion criteria, were identified and revised. Overall, 18 of the selected articles focused on human clinical trials and 79 on animal models. Only fibrin sealants, collagen patches, and omentoplasty have shown positive results in humans. Conclusions: Fibrin sealants, collagen patches, and omentoplasty are, so far, the most studied biomaterials. However, further studies are required to confirm these findings before definite recommendations can be made. (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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