Evaluation of Inflammation in the Peripheral Multiple Sclerosis Retina Using Ultra-Widefield Optical Coherence Tomography: A Pilot Study.
| Autor: | O'Riordan MM, Cahill MT, Campbell M, Kearney H |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Ophthalmic surgery, lasers & imaging retina [Ophthalmic Surg Lasers Imaging Retina] 2023 Oct; Vol. 54 (10), pp. 586-588. Date of Electronic Publication: 2023 Sep 01. |
| DOI: | 10.3928/23258160-20230825-01 |
| Abstrakt: | Background and Objective: Reports of fundus fluorescein angiography (FFA) in active multiple sclerosis (MS) have shown peripheral perivenous sheathing. We sought to assess the feasibility of ultra-widefield (UWF) FFA and optical coherence tomography (OCT) in assessing the peripheral retina in MS. Materials and Methods: Participants with MS and healthy controls underwent bilateral UWF fundus photography and FFA. Swept-source OCTs were captured centrally, peripherally, and to delineate any abnormalities visualized. Results: We recruited five people with relapsing remitting MS, with a mean age of 36.9 (± 9.9), mean disease duration of 11 years (± 6.3), and a median expanded disability status score of 0.75 (0 to 2.5). In all MS participants, the disease was not active clinically or radiologically. Using UWF-FFA and OCT, we did not detect clear evidence of peripheral retinal abnormalities, which is consistent with the participants having inactive MS. Conclusion: A pilot study using UWF-FFA and peripheral OCT to examine the retina in MS suggests that it may be useful to perform a larger prospective longitudinal study to establish its potential as a monitor of disease activity. [ Ophthalmic Surg Lasers Imaging Retina 2023;54:586-588.] . |
| Databáze: | MEDLINE |
| Externí odkaz: |
|