Post-PICU sleep efficiency and quality of life in infants and toddlers with acquired brain injury.

Autor:	Klapp JM; Pediatric Critical Care and Neurotrauma Recovery Program, Oregon Health & Science University, Portland, Oregon., Hall TA; Pediatric Critical Care and Neurotrauma Recovery Program, Oregon Health & Science University, Portland, Oregon.; Department of Pediatrics, Division of Pediatric Psychology, Oregon Health & Science University, Portland, Oregon., Riley AR; Department of Pediatrics, Division of Pediatric Psychology, Oregon Health & Science University, Portland, Oregon., Janzen D; Department of Pediatrics, Division of Pediatric Psychology, Oregon Health & Science University, Portland, Oregon., Williams CN; Pediatric Critical Care and Neurotrauma Recovery Program, Oregon Health & Science University, Portland, Oregon.; Department of Pediatrics, Division of Pediatric Critical Care, Oregon Health & Science University, Portland, Oregon.
Jazyk:	angličtina
Zdroj:	Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine [J Clin Sleep Med] 2024 Jan 01; Vol. 20 (1), pp. 75-83.
DOI:	10.5664/jcsm.10798
Abstrakt:	Study Objectives: We aimed to investigate the use of sleep efficiency (SE) as a measure of sleep disturbance in infants and toddlers with acquired brain injury (ABI) and evaluate associations between SE and child health-related quality of life and family outcomes. Methods: Retrospective cohort study of 101 children ages 3-36 months who survived critical care for ABI. SE was quantified from the Brief Infant Sleep Questionnaire as a ratio of nighttime sleep to total time in bed; poor SE was defined as < 80%. Outcome measures included the Pediatric Quality of Life Inventory Core Total Score (health-related quality of life) and Family Impact Module Total Score. Spearman's correlation quantified associations between SE and outcomes. Multivariable linear regression tested association between poor SE and health-related quality of life controlling for significant covariates (age, diagnosis, comorbidities, worsening Functional Status Scale). Results: Following ABI, median SE was 91.7 (interquartile range = 83.3, 95.5). Nineteen (19%) children had poor SE (< 80%). SE correlated significantly with quality of life (Spearman's correlation = .307) and Family Impact Module (Spearman's correlation = .309; both P < .01). When controlling for covariates, poor SE significantly increased risk for lower health-related quality of life (β-coefficient = -7.0; 95% confidence interval= -13.4, -0.6). Conclusions: One in five infants and young children with ABI have poor SE that is associated with poorer child and family health outcomes. Our study underscores the potential importance of sleep following ABI to optimize recovery and the need for additional investigation of SE in infants and young children. Citation: Klapp JM, Hall TA, Riley AR, Janzen D, Williams CN. Post-PICU sleep efficiency and quality of life in infants and toddlers with acquired brain injury. J Clin Sleep Med . 2024;20(1):75-83. (© 2024 American Academy of Sleep Medicine.)
Databáze:	MEDLINE
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